The Expanding World of Methylotrophic Metabolism

被引:316
作者
Chistoserdova, Ludmila [1 ]
Kalyuzhnaya, Marina G. [2 ]
Lidstrom, Mary E. [1 ,2 ]
机构
[1] Univ Washington, Dept Chem Engn, Seattle, WA 98195 USA
[2] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
关键词
methylotrophy; biochemistry; physiology; genomics; ecology; METHYLOBACTERIUM-EXTORQUENS AM1; TERT-BUTYL ETHER; METHYLMALONYL-COA MUTASE; COMMUNITY-LEVEL ANALYSIS; ACETIC-ACID BACTERIUM; METHANE OXIDATION; SP-NOV; GEN; NOV; GENOME SEQUENCE; ENVIRONMENTAL DETECTION;
D O I
10.1146/annurev.micro.091208.073600
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In the past few years, the field of methylotrophy has undergone a significant transformation in terms of discovery of novel types of methylotrophs, novel modes of methylotrophy, and novel metabolic pathways. This time has also been marked by the resolution of long-standing questions regarding methylotrophy and the challenge of long-standing dogmas. This chapter is not intended to provide a comprehensive review of metabolism of methylotrophic bacteria. Instead we focus on significant recent discoveries that are both refining and transforming the current understanding of methylotrophy as a metabolic phenomenon. We also review new directions in methylotroph ecology that improve our understanding of the role of methylotrophy in global biogeochemical processes, along with an outlook for the future challenges in the field.
引用
收藏
页码:477 / 499
页数:23
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