Development of 2,6-carboxy-substituted boron dipyrromethene (BODIPY) as a novel scaffold of ratiometric fluorescent probes for live cell imaging

被引：77

作者：

Komatsu, Toru ^{[1
,3
]}

Urano, Yasuteru ^{[1
]}

Fujikawa, Yuuta ^{[1
,3
]}

Kobayashi, Tomonori ^{[1
,3
]}

Kojima, Hirotatsu ^{[2
]}

Terai, Takuya ^{[1
]}

Hanaoka, Kenjiro ^{[1
]}

Nagano, Tetsuo ^{[1
,2
,3
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

[2] Univ Tokyo, Chem Biol Res Initiat, Tokyo 1130033, Japan

[3] Japan Sci & Technol Agcy, CREST, Tokyo, Japan

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 45期

关键词：

RESONANCE; DESIGN; DYES;

D O I：

10.1039/b917209b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ratiometric fluorescent probes based on boron dipyrromethene (BODIPY) were developed based on a novel design strategy, in which a change of the electron-withdrawing character of the 2,6-substituents resulting from reaction with a target molecule generates a fluorescence wavelength change.

引用

页码：7015 / 7017

页数：3

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