Sporadic acute hepatitis E in the United Kingdom: an underdiagnosed phenomenon?

被引：53

作者：

McCrudden, R

O'Connell, S

Farrant, T

Beaton, S

Iredale, JP

Fine, D

机构：

[1] Southampton Gen Hosp, Div Cell & Mol Med, Southampton SO16 6YD, Hants, England

[2] Southampton Gen Hosp, Dept Microbiol, Southampton SO9 4XY, Hants, England

[3] Southampton Gen Hosp, Publ Hlth Lab, Southampton SO9 4XY, Hants, England

[4] Southampton & SW Hampshire Hlth Author, Southampton SO16 4GX, Hants, England

[5] Southampton Gen Hosp, Dept Gastroenterol, Southampton SO9 4XY, Hants, England

来源：

GUT | 2000年 / 46卷 / 05期

关键词：

hepatitis E; viral hepatitis; epidemiology;

D O I：

10.1136/gut.46.5.732

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background-Hepatitis E (HEV) is the primary cause of enterically transmitted non-A non-B hepatitis worldwide. Case reports of HEV in individuals in the United Kingdom relate to travel to endemic areas or contact with individuals who have visited these areas. Case reports-Four individuals presented with acute hepatitis to a hepatology clinic in a teaching hospital. Serology confirmed acute hepatitis E in all four. Investigation by the Communicable Disease Control Department established no links between the cases, no travel to an endemic area, and no contacts. Conclusion-Contrary to current belief, community acquired hepatitis E virus infection occurs sporadically in the United Kingdom and should be considered as a cause of seronegative hepatitis.

引用

页码：732 / 733

页数：2

共 14 条

[1] COMMUNITY-ACQUIRED VIRAL-HEPATITIS IN NEW-ZEALAND - A CASE OF SPORADIC HEPATITIS-E VIRUS-INFECTION [J].

CHAPMAN, BA ;

BURT, MJ ;

WILKINSON, ID ;

SCHOUSBOE, MI .

AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 1993, 23 (06) :722-723

[2] HEPATITIS TYPE-E IN A FRENCH POPULATION - DETECTION OF ANTI-HEV BY A SYNTHETIC PEPTIDE-BASED ENZYME-LINKED-IMMUNOSORBENT-ASSAY [J].

COURSAGET, P ;

DEPRIL, N ;

BUISSON, Y ;

MOLINIE, C ;

ROUE, R .

RESEARCH IN VIROLOGY, 1994, 145 (01) :51-57

[3] EPIDEMIC NON-A, NON-B HEPATITIS IN PATIENTS FROM PAKISTAN [J].

DECOCK, KM ;

BRADLEY, DW ;

SANDFORD, NL ;

GOVINDARAJAN, S ;

MAYNARD, JE ;

REDEKER, AG .

ANNALS OF INTERNAL MEDICINE, 1987, 106 (02) :227-230

[4] LOCALLY ACQUIRED HEPATITIS-E IN THE NORTHERN-TERRITORY OF AUSTRALIA [J].

HEATH, TCB ;

BURROW, JNC ;

CURRIE, BJ ;

BOWDEN, FJ ;

FISHER, DA ;

DEMEDIUK, BH ;

LOCARNINI, SA ;

ANDERSON, DA .

MEDICAL JOURNAL OF AUSTRALIA, 1995, 162 (06) :318-319

[5]

Herrera J. L., 1993, Morbidity and Mortality Weekly Report, V42, P1

[6]

KWO PY, 1995, HEPATOLOGY, V22, P304

[7] Hepatitis E [J].

Mast, EE ;

Purdy, MA ;

Krawczynski, K .

BAILLIERES CLINICAL GASTROENTEROLOGY, 1996, 10 (02) :227-242

[8]

MUNOZ SJ, 1992, HEPATOLOGY, V16, pA76

[9] HEPATITIS-C AND HEPATITIS-E IN NON-A NON-B FULMINANT HEPATIC-FAILURE - A POLYMERASE CHAIN-REACTION AND SEROLOGICAL STUDY [J].

SALLIE, R ;

SILVA, AE ;

PURDY, M ;

SMITH, H ;

MCCAUSTLAND, K ;

TIBBS, C ;

PORTMANN, B ;

EDDLESTON, A ;

BRADLEY, D ;

WILLIAMS, R .

JOURNAL OF HEPATOLOGY, 1994, 20 (05) :580-588

[10] FULMINANT HEPATIC-FAILURE RESULTING FROM COEXISTENT WILSONS-DISEASE AND HEPATITIS-E [J].

SALLIE, R ;

CHIYENDE, J ;

TAN, KC ;

BRADLEY, D ;

PORTMANN, B ;

WILLIAMS, R ;

MOWAT, AP ;

MIELIVERGANI, G .

GUT, 1994, 35 (06) :849-853

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