Sporadic acute hepatitis E in the United Kingdom: an underdiagnosed phenomenon?

被引:53
作者
McCrudden, R
O'Connell, S
Farrant, T
Beaton, S
Iredale, JP
Fine, D
机构
[1] Southampton Gen Hosp, Div Cell & Mol Med, Southampton SO16 6YD, Hants, England
[2] Southampton Gen Hosp, Dept Microbiol, Southampton SO9 4XY, Hants, England
[3] Southampton Gen Hosp, Publ Hlth Lab, Southampton SO9 4XY, Hants, England
[4] Southampton & SW Hampshire Hlth Author, Southampton SO16 4GX, Hants, England
[5] Southampton Gen Hosp, Dept Gastroenterol, Southampton SO9 4XY, Hants, England
关键词
hepatitis E; viral hepatitis; epidemiology;
D O I
10.1136/gut.46.5.732
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background-Hepatitis E (HEV) is the primary cause of enterically transmitted non-A non-B hepatitis worldwide. Case reports of HEV in individuals in the United Kingdom relate to travel to endemic areas or contact with individuals who have visited these areas. Case reports-Four individuals presented with acute hepatitis to a hepatology clinic in a teaching hospital. Serology confirmed acute hepatitis E in all four. Investigation by the Communicable Disease Control Department established no links between the cases, no travel to an endemic area, and no contacts. Conclusion-Contrary to current belief, community acquired hepatitis E virus infection occurs sporadically in the United Kingdom and should be considered as a cause of seronegative hepatitis.
引用
收藏
页码:732 / 733
页数:2
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