Parsing the prosencephalon

被引：125

作者：

Rallu, M

Corbin, JG

Fishell, G

机构：

[1] NYU, Ctr Med, Skirball Inst Biomol Med, Dev Genet Program, New York, NY 10016 USA

[2] NYU, Ctr Med, Skirball Inst Biomol Med, Dept Cell Biol, New York, NY 10016 USA

来源：

NATURE REVIEWS NEUROSCIENCE | 2002年 / 3卷 / 12期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nrn989

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The forebrain, or prosencephalon, consists of the diencephalon and the telencephalon. The diencephalon is the conduit for ascending sensory information, whereas the telencephalon is the highest-order processor of neural function, and is consequently the most complex region of the nervous system. In this review, we discuss how fate restrictions, starting from the induction of neural character, result in the sequential specification of anterior neural tissue, forebrain and telencephalon, and finally dorsoventral patterning. Rather than relying on novel signalling pathways, the complexity of the mature brain seems to result from the unique ordering of signals used widely during development.

引用

页码：943 / 951

页数：9

共 105 条

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