Inhibitive Effects of Alkyl Gallates on Hyaluronidase and Collagenase

被引：32

作者：

Barla, Florin ^{[1
]}

Higashijima, Hayato ^{[1
]}

Funai, Shingo ^{[1
]}

Sugimoto, Keiichiro ^{[1
]}

Harada, Naoki ^{[1
]}

Yamaji, Ryoichi ^{[1
]}

Fujita, Tomoyuki ^{[2
]}

Nakano, Yoshihisa ^{[1
,3
]}

Inui, Hiroshi ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Dept Appl Biol Chem, Grad Sch Life & Environm Sci, Osaka 5998531, Japan

[2] Shinshu Univ, Dept Sci Funct Foods, Grad Sch Agr, Nagano 3994598, Japan

[3] Osaka Womens Jr Coll, Osaka 5838558, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2009年 / 73卷 / 10期

关键词：

alkyl gallates; hyaluronidase inhibitory activity; collagenase inhibitory activity; antioxidant activity; MOLECULAR DESIGN; ANTIFUNGAL AGENTS; FLAVONOIDS; PROTEIN; TANNINS;

D O I：

10.1271/bbb.90365

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

A series of the gallate esters of n-alkanols (C-1-C-12) was examined to determine their inhibitory activities against hyaluronidase and collagenase. Hexyl, heptyl, octyl, nonyl, and decyl gallates inhibited both hyaluronidase and collagenase, and the most potent inhibitor was octyl gallate against both enzymes. Octyl 3,5-dihydroxybenzoate showed inhibitory effects on hyaluronidase, whereas collagenase was inhibited by octyl 3,4-dihydroxybenzoate.

引用

页码：2335 / 2337

页数：3

共 20 条

[1]

EVALUATION OF THE ANTIOXIDANT AND PROOXIDANT ACTIONS OF GALLIC ACID AND ITS DERIVATIVES [J].

ARUOMA, OI ;

MURCIA, A ;

BUTLER, J ;

HALLIWELL, B .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1993, 41 (11) :1880-1885

[2]

Lipoxygenase inhibitory activity of octyl gallate [J].

Ha, TJ ;

Nihei, KI ;

Kubo, I .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (10) :3177-3181

[3]

Collagenase activity and protein hydrolysis as related to spoilage of iced cod (Gadus morhua) [J].

Hernández-Herrero, MM ;

Duflos, G ;

Malle, P ;

Bouquelet, S .

FOOD RESEARCH INTERNATIONAL, 2003, 36 (02) :141-147

[4]

Herrmann G, 1993, Exp Dermatol, V2, P92, DOI 10.1111/j.1600-0625.1993.tb00015.x

[5]

KAKEGAWA H, 1985, CHEM PHARM BULL, V33, P642

[6]

Antibacterial activity of akyl gallates against Bacillus subtilis [J].

Kubo, I ;

Fujita, K ;

Nihei, K ;

Nihei, A .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (05) :1072-1076

[7]

Molecular design of antibrowning agents [J].

Kubo, I ;

Kinst-Hori, I ;

Kubo, Y ;

Yamagiwa, Y ;

Kamikawa, T ;

Haraguchi, H .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (04) :1393-1399

[8]

Molecular design of antifungal agents [J].

Kubo, I ;

Xiao, P ;

Nihei, K ;

Fujita, K ;

Yamagiwa, Y ;

Kamikawa, T .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2002, 50 (14) :3992-3998

[9]

Inhibition of mammalian collagenase, matrix metalloproteinase-1, by naturally-occurring flavonoids [J].

Lim, Hyun ;

Kim, Hyun Pyo .

PLANTA MEDICA, 2007, 73 (12) :1267-1274

[10]

Molecular design of multifunctional food additives: Antioxidative antifungal agents [J].

Nihei, K ;

Nihei, A ;

Kubo, I .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (16) :5011-5020

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