Epilepsy: synapses stuck in childhood

被引：7

作者：

Caleo, Matteo ^{[1
]}

机构：

[1] CNR, Ist Neurosci, I-56100 Pisa, Italy

来源：

NATURE MEDICINE | 2009年 / 15卷 / 10期

关键词：

AUTOSOMAL-DOMINANT; LGI1; MUTATIONS; ENCODES; BRAIN;

D O I：

10.1038/nm1009-1126

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Mouse experiments show how mutation of a gene involved in human epilepsy causes hyperexcitability of the neuronal network (pages 1208-1214). The mutations interfere with the maturation of excitatory synapses during postnatal development.

引用

页码：1126 / 1127

页数：2

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