Sperm and oocyte donor selection and management:: experience of a 10 year follow-up of more than 2100 candidates

被引:81
作者
Garrido, N
Zuzuarregui, JL
Meseguer, M
Simón, C
Remohí, J
Pellicer, A
机构
[1] Inst Valenciano Infertil, Androl Lab & Semen Bank, Valencia 46020, Spain
[2] Univ Valencia, Sch Med, Dept Paediat Obstet & Gynaecol, Valencia, Spain
[3] Univ Valencia, FIVIER, Valencia, Spain
[4] Hosp Dr Peset, Valencia, Spain
关键词
oocyte donors; sexually transmitted diseases; sperm donors;
D O I
10.1093/humrep/17.12.3142
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background: The main concerns for couples undergoing assisted reproduction treatment using donor gametes are the possibilities of acquiring infectious diseases and of transmitting genetic disorders to the progeny. They are also frequently concerned and interested in the cultural and psychological background of the donors. Our aim was to examine the current prevalence of genetic alterations and infectious diseases in our sperm and oocyte donor population., and to review our experience in the management of donors and candidates during the last 10 years. Methods and Results: Routine blood analyses, semen and vaginal cultures together with complete medical, psychological and genetic histories were examined retrospectively. Our results clearly show that the frequency of sexually transmitted diseases and genetic disorders is comparable with both the frequency present in the population requiring infertility treatments and the general population. Conclusions: The screening procedure applied to all the candidates sufficiently minimizes any risk to the gamete receiver and the offspring.
引用
收藏
页码:3142 / 3148
页数:7
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