Efficient and direct synthesis of poly-substituted indeno[1,2-b]quinolines assisted by p-toluene sulfonic acid using high-temperature water and microwave heating via one-pot, three-component reaction

被引:75
作者
Tu, Shu-Jiang [1 ]
Jiang, Bo [1 ]
Zhang, Jun-Yong [1 ]
Jia, Run-Hong [1 ]
Zhang, Yan [1 ]
Yao, Chang-Sheng [1 ]
机构
[1] Xuzhou Normal Univ, Key Lab Biotechnol Med Plants, Dept Chem, Xuzhou 211116, Jiangsu, Peoples R China
关键词
D O I
10.1039/b611462h
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reactions of aldehydes, 1,3-indanedione and enaminones were successfully carried out using p-toluene sulfonic acid (p-TsOH) as a catalyst and high-temperature water as a solvent under microwave irradiation. This method provided several advantages such as rapid reaction times, high yields, and a simple workup procedure. In addition, a possible mechanism to account for the reaction was proposed.
引用
收藏
页码:3980 / 3985
页数:6
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