Development, dimensions, reliability and validity of the novel Manchester COPD fatigue scale

被引:38
作者
Al-shair, K. [1 ]
Kolsum, U.
Berry, P. [2 ]
Smith, J.
Caress, A. [3 ]
Singh, D.
Vestbo, J.
机构
[1] Univ Manchester, S Manchester Univ Hosp NHS Fdn Trust, Educ & Res Ctr, Resp Res Grp, Manchester M23 9LT, Lancs, England
[2] GlaxoSmithKline, Global Hlth Outcomes, London, England
[3] Univ Manchester, Sch Nursing Midwifery & Social Work, Manchester M23 9LT, Lancs, England
基金
英国医学研究理事会;
关键词
OBSTRUCTIVE PULMONARY-DISEASE; QUALITY-OF-LIFE; HEALTH-STATUS; QUESTIONNAIRE; DEPRESSION; VALIDATION; SYMPTOMS; DYSPNEA;
D O I
10.1136/thx.2009.118109
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Introduction: Fatigue is a prominent symptom in chronic obstructive pulmonary disease (COPD) and it has distinctive features; however, there is a need for a robust scale to measure fatigue in COPD. Methods: At baseline, 122 patients with COPD (forced expiratory volume in 1 s (FEV1) 52%, women 38%, mean age 66 years) completed a pilot fatigue scale covering a pool of 57 items and underwent a range of tests, including indicators of mood and a short general fatigue questionnaire. All patients responded to the 57-item scale and it was readministered to a subset of 30 patients. The pilot scale was first subjected to constructive validated shortening steps and then to a principal components analysis. Results: The Manchester COPD fatigue scale (MCFS) consists of 27 items, loading into three dimensions: physical, cognitive and psychosocial fatigue. Internal consistency (Cronbach's alpha=0.97) and test-retest repeatability (r=0.97, p<0.001) were tested. It had significant convergent validity, correlating with the FACIT (Functional Assessment of Chronic Illness Therapy) fatigue scale and the fatigue in Borg scale at baseline and after a 6 minute walk distance (6MWD) test (r=-0.81, 0.53 and 0.63, respectively, p<0.001). Its scores were associated with BODE, SGRQ (St George's Respiratory Questionnaire) and MRC (Medical Research Council) dyspnoea scores (r=0.46, 0.8 and 0.51, respectively, p<0.001). The scale demonstrated meaningful discriminating ability; patients who walked,350 m in a 6MWD test as well as depressed patients (>= 16 scores in the Center for Epidemiologic Study on Depression (CES-D) scale) had nearly twice as high fatigue scores as those who walked >= 350 m or were not depressed (p<0.001). Conclusion: The MCFS provides a simple, reliable and valid measurement of total and dimensional fatigue in moderate stable COPD.
引用
收藏
页码:950 / 955
页数:6
相关论文
共 35 条
[1]   Depression and its relationship with poor exercise capacity, BODE index and muscle wasting in COPD [J].
Al-shair, Khaled ;
Dockry, Rachel ;
Mallia-Milanes, Brendan ;
Kolsum, Umme ;
Singh, Dave ;
Vestbo, Jorgen .
RESPIRATORY MEDICINE, 2009, 103 (10) :1572-1579
[2]   Mortality after hospitalization for COPD [J].
Almagro, P ;
Calbo, E ;
de Echagüen, AO ;
Barreiro, B ;
Quintana, S ;
Heredia, JL ;
Garau, J .
CHEST, 2002, 121 (05) :1441-1448
[3]   Determinants and impact of fatigue in patients with chronic obstructive pulmonary disease [J].
Baghai-Ravary, Ramin ;
Quint, Jennifer K. ;
Goldring, James J. P. ;
Hurst, John R. ;
Donaldson, Gavin C. ;
Wedzicha, Jadwiga A. .
RESPIRATORY MEDICINE, 2009, 103 (02) :216-223
[4]   Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease [J].
Bestall, JC ;
Paul, EA ;
Garrod, R ;
Garnham, R ;
Jones, PW ;
Wedzicha, JA .
THORAX, 1999, 54 (07) :581-586
[5]   STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT [J].
BLAND, JM ;
ALTMAN, DG .
LANCET, 1986, 1 (8476) :307-310
[6]   PSYCHOPHYSICAL BASES OF PERCEIVED EXERTION [J].
BORG, GAV .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1982, 14 (05) :377-381
[7]   Perception of fatigue and quality of life in patients with COPD [J].
Breslin, E ;
van der Schans, C ;
Breukink, S ;
Meek, P ;
Mercer, K ;
Volz, W ;
Louie, S .
CHEST, 1998, 114 (04) :958-964
[8]   The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease [J].
Celli, BR ;
Cote, CG ;
Marin, JM ;
Casanova, C ;
de Oca, MM ;
Mendez, RA ;
Pinto Plata, V ;
Cabral, HJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (10) :1005-1012
[9]   Validation and comparison of reference equations for the 6-min walk distance test [J].
Cote, C. G. ;
Casanova, C. ;
Marin, J. M. ;
Lopez, M. V. ;
Pinto-Plata, V. ;
de Oca, M. M. ;
Dordelly, L. J. ;
Nekach, H. ;
Celli, B. R. .
EUROPEAN RESPIRATORY JOURNAL, 2008, 31 (03) :571-578
[10]   ATS statement: Guidelines for the six-minute walk test [J].
Crapo, RO ;
Casaburi, R ;
Coates, AL ;
Enright, PL ;
MacIntyre, NR ;
McKay, RT ;
Johnson, D ;
Wanger, JS ;
Zeballos, RJ ;
Bittner, V ;
Mottram, C .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (01) :111-117