Caveolin-1 and liver regeneration - Role in proliferation and lipogenesis

被引：20

作者：

Frank, Philippe G. ^{[1
]}

Lisanti, Michael P. ^{[1
]}

机构：

[1] Thomas Jefferson Univ, Dept Canc Biol, Kimmel Canc Ctr, Philadelphia, PA 19107 USA

来源：

CELL CYCLE | 2007年 / 6卷 / 02期

关键词：

caveolin; liver regeneration; lipogenesis; triglycerides; fatty acids;

D O I：

10.4161/cc.6.2.3722

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Caveolin-1 is an essential component of caveolae, which form 50-100 nm cell surface plasma membrane invaginations. Caveolin-1 has been previously implicated in the regulation of cellular proliferation and lipogenesis. Current data now suggest that caveolin-1 plays an essential role in the regulation of liver regeneration and that it is implicated in the regulation of triglyceride accumulation, which is an essential process that plays a critical role in the regulation of liver regeneration. These findings are consistent with the importance of a lipogenesis program in the regulation of liver regeneration.

引用

页码：115 / 116

页数：2

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