Convenient preparation of 2-deoxy-3,5-di-O-p-toluoyl-alpha-D-erythro-pentofuranosyl chloride

被引：79

作者：

Rolland, V ^{[1
]}

Kotera, M ^{[1
]}

Lhomme, J ^{[1
]}

机构：

[1] UNIV GRENOBLE 1,ETUD DYNAM & STRUCT SELECT LAB,CNRS,UMR 5616,F-38041 GRENOBLE,FRANCE

来源：

SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 20期

关键词：

D O I：

10.1080/00397919708007071

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By using acetyl chloride as HCl generator, the procedure for the Hoffer preparation of the alpha-chloro sugar 4a was significantly improved. The alpha-configuration of the chloro atom was confirmed by using NOE measurement. Sequential transformation of 4a to the beta-anomer and to the furfuryl derivative 6 was studied.

引用

页码：3505 / 3511

页数：7

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