Angiogenesis in atherogenesis

被引:96
作者
Herrmann, Joerg
Lerman, Lilach O.
Mukhopadhyay, Debabrata
Napoli, Claudio
Lerman, Amir
机构
[1] Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA
[2] Mayo Clin, Div Nephrol & Hypertens, Rochester, MN 55905 USA
[3] Mayo Clin, Div Biochem & Mol Biol, Rochester, MN 55905 USA
[4] Univ Naples 2, Dept Gen Pathol, Div Clin Pathol, Naples, Italy
[5] Univ Naples 2, Excellence Res Ctr Cardiovasc Dis, Sch Med 1, Naples, Italy
关键词
atherosclerosis; cancer; neovascularization; oxidative stress; pathology;
D O I
10.1161/01.ATV.0000233387.90257.9b
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Atherogenesis is the pathobiological process, which underlies atherosclerotic cardiovascular disease and evolves in the 3 stages of initiation, progression, and complication to clinical significance. Of note, this process is associated with neovascularization, and it was not until recently that the implications of angiogenesis in atherogenesis were delineated. This article gives an updated overview on this topic and briefly reflects on the similarities with neovessel formation in carcinogenesis.
引用
收藏
页码:1948 / 1957
页数:10
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