A genetic programme for neuronal connectivity

被引：26

作者：

Ghysen, A ^{[1
]}

Dambly-Chaudière, C ^{[1
]}

机构：

[1] Univ Montpellier 2, Neurogenet Lab, INSERM E0012, F-34095 Montpellier, France

来源：

TRENDS IN GENETICS | 2000年 / 16卷 / 05期

关键词：

D O I：

10.1016/S0168-9525(99)01969-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

What is the nature of the genetic programme that allows neurons to extend their axons and connect to other neurons with a high degree of specificity? Work on the sensory neurons of the fly has shown how the control of neuronal identity is embedded in the general developmental programme of the organism. The ongoing analysis of pathfinding mutants suggests plausible mechanisms for the translation of neuronal identity into axonal behaviour.

引用

页码：221 / 226

页数：6

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