Chemical engineering of RNase resistant and catalytically active hammerhead ribozymes

被引：13

作者：

Burlina, F

Favre, A

Fourrey, JL

机构：

[1] CNRS, INST CHIM SUBST NAT, F-91198 GIF SUR YVETTE, FRANCE

[2] UNIV PARIS 07, CNRS, INST JACQUES MONOD, F-75251 PARIS 05, FRANCE

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1997年 / 5卷 / 11期

关键词：

D O I：

10.1016/S0968-0896(97)00144-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1999 / 2010

页数：12

共 119 条

[1]

Akhtar S, 1992, Trends Cell Biol, V2, P139, DOI 10.1016/0962-8924(92)90100-2

[2] The global conformation of an active hammerhead RNA during the process of self-cleavage [J].

Amiri, KMA ;

Hagerman, PJ .

JOURNAL OF MOLECULAR BIOLOGY, 1996, 261 (02) :125-134

[3] GLOBAL CONFORMATION OF A SELF-CLEAVING HAMMERHEAD RNA [J].

AMIRI, KMA ;

HAGERMAN, PJ .

BIOCHEMISTRY, 1994, 33 (45) :13172-13177

[4]

AURUP H, 1995, DELIVERY STRATEGIES

[5] A kinetic and thermodynamic analysis of cleavage site mutations in the hammerhead ribozyme [J].

Baidya, N ;

Uhlenbeck, OC .

BIOCHEMISTRY, 1997, 36 (05) :1108-1114

[6] IONIC INTERACTIONS AND THE GLOBAL CONFORMATIONS OF THE HAMMERHEAD RIBOZYME [J].

BASSI, GS ;

MOLLEGAARD, NE ;

MURCHIE, AIH ;

VONKITZING, E ;

LILLEY, DMJ .

NATURE STRUCTURAL BIOLOGY, 1995, 2 (01) :45-55

[7] THE SYNTHESIS OF SPECIFIC RIBONUCLEOTIDES AND UNRELATED PHOSPHORYLATED BIOMOLECULES BY THE PHOSPHORAMIDITE METHOD [J].

BEAUCAGE, SL ;

IYER, RP .

TETRAHEDRON, 1993, 49 (46) :10441-10488

[8] NEW STRUCTURAL MOTIFS FOR HAMMERHEAD RIBOZYMES - CATALYTIC ACTIVITY OF ABASIC NUCLEOTIDE SUBSTITUTED RIBOZYMES [J].

BEIGELMAN, L ;

KARPEISKY, A ;

MATULICADAMIC, J ;

GONZALEZ, C ;

USMAN, N .

NUCLEOSIDES & NUCLEOTIDES, 1995, 14 (3-5) :907-910

[9] CHEMICAL MODIFICATION OF HAMMERHEAD RIBOZYMES - CATALYTIC ACTIVITY AND NUCLEASE RESISTANCE [J].

BEIGELMAN, L ;

MCSWIGGEN, JA ;

DRAPER, KG ;

GONZALEZ, C ;

JENSEN, K ;

KARPEISKY, AM ;

MODAK, AS ;

MATULICADAMIC, J ;

DIRENZO, AB ;

HAEBERLI, P ;

SWEEDLER, D ;

TRACZ, D ;

GRIMM, S ;

WINCOTT, FE ;

THACKRAY, VG ;

USMAN, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (43) :25702-25708

[10] SYNTHESIS OF 1-DEOXY-D-RIBOFURANOSE PHOSPHORAMIDITE AND THE INCORPORATION OF ABASIC NUCLEOTIDES IN STEM-LOOP-II OF A HAMMERHEAD RIBOZYME [J].

BEIGELMAN, L ;

KARPEISKY, A ;

USMAN, N .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (14) :1715-1720

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