Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole

被引：32

作者：

Bradley, PJ ^{[1
]}

Hsieh, CL ^{[1
]}

Boothroyd, JC ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Microbiol & Immunol, Stanford, CA 94305 USA

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2002年 / 125卷 / 1-2期

关键词：

Toxoplasma gondii; ROP1; rhoptry; processing;

D O I：

10.1016/S0166-6851(02)00162-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：189 / 193

页数：5

共 19 条

[1] THE TOXOPLASMA-GONDII RHOPTRY PROTEIN ROP-2 IS INSERTED INTO THE PARASITOPHOROUS VACUOLE MEMBRANE, SURROUNDING THE INTRACELLULAR PARASITE, AND IS EXPOSED TO THE HOST-CELL CYTOPLASM [J].

BECKERS, CJM ;

DUBREMETZ, JF ;

MERCEREAUPUIJALON, O ;

JOINER, KA .

JOURNAL OF CELL BIOLOGY, 1994, 127 (04) :947-961

[2] The pro region of Toxoplasma ROP1 is a rhoptry-targeting signal [J].

Bradley, PJ ;

Boothroyd, JC .

INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2001, 31 (11) :1177-1186

[3] Identification of the pro-mature processing site of Toxoplasma ROP1 by mass spectrometry [J].

Bradley, PJ ;

Boothroyd, JC .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1999, 100 (01) :103-109

[4]

Carruthers VB, 1997, EUR J CELL BIOL, V73, P114

[5]

Carruthers Vern B., 1999, Parasitology International, V48, P1

[6]

Engel JC, 1998, J CELL SCI, V111, P597

[7]

Frenkel J. K., 1973, The coccidia,, P343

[8] Toxoplasma gondii homologue of plasmodium apical membrane antigen 1 is involved in invasion of host cells [J].

Hehl, AB ;

Lekutis, C ;

Grigg, ME ;

Bradley, PJ ;

Dubremetz, JF ;

Ortega-Barria, E ;

Boothroyd, JC .

INFECTION AND IMMUNITY, 2000, 68 (12) :7078-7086

[9] Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms. [J].

Hoppe, HC ;

Ngô, HM ;

Yang, M ;

Joiner, KA .

NATURE CELL BIOLOGY, 2000, 2 (07) :449-456

[10] TOXOPLASMA-GONDII - A PROTOZOAN FOR THE 90S [J].

JOINER, KA ;

DUBREMETZ, JF .

INFECTION AND IMMUNITY, 1993, 61 (04) :1169-1172

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