Prevalence of Symptomatic and Asymptomatic Peripheral Arterial Disease and the Value of the Ankle-brachial Index to Stratify Cardiovascular Risk

被引:123
作者
Ramos, R. [1 ,2 ,3 ]
Quesada, M. [1 ,2 ,4 ]
Solanas, P. [1 ,2 ]
Subirana, I. [3 ]
Sala, J. [5 ,6 ]
Vila, J. [3 ]
Masia, R. [5 ,6 ]
Cerezo, C. [1 ,2 ]
Elosua, R. [3 ]
Grau, M. [3 ,4 ]
Cordon, F. [1 ,2 ]
Juvinya, D. [7 ]
Fito, M. [3 ]
Isabel Covas, M. [3 ]
Clara, A. [8 ]
Angel Munoz, M. [4 ,9 ]
Marrugat, J. [3 ]
机构
[1] Inst Catala Salut, IDIAP Jordi Gol, Unitat Rec, Girona, Spain
[2] Inst Catala Salut, IDIAP Jordi Gol, Unitat Docent Med Familia Girona, Girona, Spain
[3] IMIM, Cardiovasc Epidemiol & Genet Res Grp, ULEC, Res Inflammatory & Cardiovasc Disorders Program, Barcelona, Spain
[4] Univ Autonoma Barcelona, Programa Doctorat Salut Publ & Metodol Recerca Bi, E-08193 Barcelona, Spain
[5] Hosp Girona Josep Trueta, Serv Cardiol, Girona, Spain
[6] Hosp Girona Josep Trueta, Unitat Coronaria, Girona, Spain
[7] Univ Girona, Girona, Spain
[8] Hosp del Mar, Serv Angiol & Cirurgia Vasc, Barcelona, Spain
[9] Inst Catala Salut, Area Basica Salut Montornes Montmelo, Girona, Spain
关键词
Peripheral vascular diseases; Risk assessment; Primary prevention; Risk factors; OCCLUSIVE DISEASE; ASSOCIATION; POPULATION; MANAGEMENT; EVENTS; TRIAL;
D O I
10.1016/j.ejvs.2009.04.013
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: To determine the prevalence of ankle-brachial index (ABI) < 0.9 and symptomatic peripheral arterial disease (PAD), association with cardiovascular risk factors (CVRF), and impact of adding ABI measurement to coronary heart disease (CHD) risk screening. Design: Population-based cross-sectional survey of 6262 participants aged 35-79 in Girona, Spain. Methods: Standardized measurements (CVRF, ABI, 10-year CHD risk) and history of intermittent claudication (IC), CHD, and stroke were recorded. ABI < 0.9 was considered equivalent to moderate-to-high CHD risk (>= 10%). Results: ABI < 0.9 prevalence was 4.5%. Only 0.62% presented low ABI and IC. Age, current smoker, cardiovascular disease, and uncontrolled hypertension independently associated with ABI < 0.9 in both sexes; IC was also associated in men and diabetes in women. Among participants 35-74 free of cardiovascular disease, 6.1% showed moderate-to-high 10-year CHD risk; adding ABI measurement yielded 8.7%. Conversely, the risk function identified 16.8% of these participants as having 10-year CHID risk > 10%. In participants 75-79 free of cardiovascular disease, the prevalence of ABI < 0.9 (i.e., CHD risk >= 10%) was 11.9%. Conclusions: ABI < 0.9 is relatively frequent in those 35-79, particularly over 74. However, IC and CHD risk >= 10% indicators are often missing. Adding ABI measurement to CHD-risk screening better identifies moderate-to-high cardiovascular risk patients. (C) 2009 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:305 / 311
页数:7
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