Intensity modulated radiation therapy: a clinical review

被引:137
作者
Nutting, C
Dearnaley, DP
Webb, S
机构
[1] Inst Canc Res, Acad Unit Radiotherapy & Oncol, Sutton SM2 5PT, Surrey, England
[2] Inst Canc Res, Dept Phys, Sutton SM2 5PT, Surrey, England
[3] Royal Marsden NHS Trust, Sutton SM2 5PT, Surrey, England
关键词
D O I
10.1259/bjr.73.869.10884741
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Intensity modulated radiotherapy represents a significant advance in conformal radiotherapy. In particular, it allows the delivery of dose distributions with concave isodose profiles such that radiosensitive normal tissue close to, or even within a concavity of, a tumour may be spared from radiation injury. This article reviews the clinical application of this technique to date, and discusses the practical issues of treatment planning and delivery from the clinician's perspective.
引用
收藏
页码:459 / 469
页数:11
相关论文
共 82 条
[51]   Tomotherapy [J].
Mackie, TR ;
Balog, J ;
Ruchala, K ;
Shepard, D ;
Aldridge, S ;
Fitchard, E ;
Reckwerdt, P ;
Olivera, G ;
McNutt, T ;
Mehta, M .
SEMINARS IN RADIATION ONCOLOGY, 1999, 9 (01) :108-117
[52]   TOMOTHERAPY - A NEW CONCEPT FOR THE DELIVERY OF DYNAMIC CONFORMAL RADIOTHERAPY [J].
MACKIE, TR ;
HOLMES, T ;
SWERDLOFF, S ;
RECKWERDT, P ;
DEASY, JO ;
YANG, J ;
PALIWAL, B ;
KINSELLA, T .
MEDICAL PHYSICS, 1993, 20 (06) :1709-1719
[53]  
Marsh L, 1996, Med Dosim, V21, P7, DOI 10.1016/0958-3947(95)02048-9
[54]   Dose-volume complication analysis for visual pathway structures of patients with advanced paranasal sinus tumors [J].
Martel, MK ;
Sandler, HM ;
Cornblath, WT ;
Marsh, LH ;
Hazuka, MB ;
Roa, WH ;
Fraass, BA ;
Lichter, AS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 38 (02) :273-284
[55]  
MARTEL MK, 1997, RADIOTHER ONCOL, V47, P185
[56]   Potential clinical efficacy of intensity-modulated conformal therapy [J].
Meeks, SL ;
Buatti, JM ;
Bova, FJ ;
Friedman, WA ;
Mendenhall, WM ;
Zlotecki, RA .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 40 (02) :483-495
[57]   Prospective clinical evaluation of an electronic portal imaging device [J].
Michalski, JM ;
Graham, MV ;
Bosch, WR ;
Wong, J ;
Gerber, RL ;
Cheng, A ;
Tinger, A ;
Valicenti, RK .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1996, 34 (04) :943-951
[58]  
NEIMIERKO A, 1993, INT J RADIAT ONCOL, V25, P135
[59]   Independent verification using portal imaging of intensity-modulated beam delivery by the dynamic MLC technique [J].
Partridge, M ;
Evans, PM ;
Mosleh-Shirazi, A ;
Convery, D .
MEDICAL PHYSICS, 1998, 25 (10) :1872-1879
[60]  
Purdy JA, 1997, SEMIN ONCOL, V24, P655