Chiral Amplification with a Stereodynamic Triaryl Probe: Assignment of the Absolute Configuration and Enantiomeric Excess of Amino Alcohols

被引：87

作者：

Ghosn, Marwan W. ^{[1
]}

Wolf, Christian ^{[1
]}

机构：

[1] Georgetown Univ, Dept Chem, Washington, DC 20057 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 45期

基金：

美国国家科学基金会;

关键词：

INDUCED CIRCULAR-DICHROISM; HIGHLY CONSTRAINED 1,8-BIS(2,2'-DIALKYL-4,4'-DIQUINOLYL)NAPHTHALENES; CYCLODEXTRIN INCLUSION COMPLEXES; INDUCED AXIAL CHIRALITY; CARBOXYLIC-ACIDS; CHROMOPHORE; HOST; FLUOROSENSOR; RECOGNITION; MECHANISM;

D O I：

10.1021/ja907741v

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A stereodynamic, axially chiral triaryl probe is locked into a single conformation upon condensation with two amino alcohol substrates. The welt-defined chiral amplification in the diimines formed results in intense Cotton effects at high wavelengths that can be used for in situ CD analysis of the absolute configuration and of cyclic and acyclic substrates.

引用

页码：16360 / +

页数：4

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