Vascular dementia among elderly Arabs in Wadi Ara

被引:18
作者
Bowirrat, A
Friedland, RP
Korczyn, AD [1 ]
机构
[1] Tel Aviv Univ, Sch Med, IL-69978 Ramat Aviv, Israel
[2] Case Western Reserve Univ, Dept Neurol, Cleveland, OH 44106 USA
关键词
vascular dementia; Alzheimer's disease; epidemiology; risk factors; illiteracy;
D O I
10.1016/S0022-510X(02)00269-1
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Dementia of the Alzheimer type (DAT) and vascular dementia (VaD) are the two major subtypes of dementia. In our epidemiological study of DAT in an Arab community in Wadi Ara, Israel, we found a high prevalence of late onset DAT. Illiteracy, smoking, diabetes mellitus (DM) and hypertension are very frequent in Wadi Ara. These factors led us to study the prevalence of VaD and various risk factors in this population. All people aged 60 years or older (n = 823) in a defined region were examined for identification of DAT and VaD (DSM-IV criteria), using clinical examinations and a semi-structured questionnaire for detecting cognitive dysfunction. We identified 49 demented patients (29 males) fulfilling criteria of VaD with a prevalence rate of 49/823 (5.9%), compared to 168/823 (20.5%) for DAT. All had suffered from strokes. Male gender and hypertension were more common among VaD cases. Illiteracy was significantly more common among VaD patients than among healthy subjects (79.6% vs. 40.2%, P = 0.001) but less common than among DAT patients (94.6%, P = 0.001). Thus, our results show that VaD constitutes about 22% of the total dementia population in Wadi Ara. We confirm the association between VaD, illiteracy and hypertension. Smoking and gender do not represent risk factors for VaD in this population. While suggestive, DM is not a statistically significant risk factor for VaD. (C) 2002 Published by Elsevier Science B.V.
引用
收藏
页码:73 / 76
页数:4
相关论文
共 17 条
[1]   The very high prevalence of AD in an Arab population is not explained by APOE ε4 allele frequency [J].
Bowirrat, A ;
Friedland, RP ;
Chapman, J ;
Korczyn, AD .
NEUROLOGY, 2000, 55 (05) :731-731
[2]   Prevalence of Alzheimer's type dementia in an elderly Arab population [J].
Bowirrat, A ;
Treves, TA ;
Friedland, RP ;
Korczyn, AD .
EUROPEAN JOURNAL OF NEUROLOGY, 2001, 8 (02) :119-123
[3]   Dementia after first stroke [J].
Censori, B ;
Manara, O ;
Agostinis, C ;
Camerlingo, M ;
Casto, L ;
Galavotti, B ;
Partziguian, T ;
Servalli, MC ;
Cesana, B ;
Belloni, G ;
Mamoli, A .
STROKE, 1996, 27 (07) :1205-1210
[4]   Frequency and clinical determinants of dementia after ischemic stroke [J].
Desmond, DW ;
Moroney, JT ;
Paik, MC ;
Sano, M ;
Mohr, JP ;
Aboumatar, S ;
Tseng, CL ;
Chan, S ;
Williams, JBW ;
Remien, RH ;
Hauser, WA ;
Stern, Y .
NEUROLOGY, 2000, 54 (05) :1124-1131
[5]   PREVALENCE OF ALZHEIMERS-DISEASE AND OTHER DEMENTIAS IN AN ELDERLY URBAN-POPULATION - RELATIONSHIP WITH AGE, SEX, AND EDUCATION [J].
FRATIGLIONI, L ;
GRUT, M ;
FORSELL, Y ;
VIITANEN, M ;
GRAFSTROM, M ;
HOLMEN, K ;
ERICSSON, K ;
BACKMAN, L ;
AHLBOM, A ;
WINBLAD, B .
NEUROLOGY, 1991, 41 (12) :1886-1892
[6]   LEUKOARAIOSIS [J].
HACHINSKI, VC ;
POTTER, P ;
MERSKEY, H .
ARCHIVES OF NEUROLOGY, 1987, 44 (01) :21-23
[7]  
LAURNER LJ, 1995, JAMA-J AM MED ASSOC, V274, P1846
[8]   Diagnostic and Statistical Manual of Mental Disorders [J].
Mittal, Vijay A. ;
Walker, Elaine F. .
PSYCHIATRY RESEARCH, 2011, 189 (01) :158-159
[9]   J-curve relation between blood pressure and decline in cognitive function in older people living in community, Japan [J].
Okumiya, K ;
Matsubayashi, K ;
Wada, T ;
Osaki, Y ;
Doi, Y ;
Ozawa, T .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1997, 45 (08) :1032-1033
[10]   THE PREVALENCE OF VASCULAR DEMENTIA IN EUROPE - FACTS AND FRAGMENTS FROM 1980-1990 STUDIES [J].
ROCCA, WA ;
HOFMAN, A ;
BRAYNE, C ;
BRETELER, MMB ;
CLARKE, M ;
COPELAND, JRM ;
DARTIGUES, JF ;
ENGEDAL, K ;
HAGNELL, O ;
HEEREN, TJ ;
JONKER, C ;
LINDESAY, J ;
LOBO, A ;
MANN, AH ;
MOLSA, PK ;
MORGAN, K ;
OCONNOR, DW ;
DROUX, AD ;
SULKAVA, R ;
KAY, DWK ;
AMADUCCI, L .
ANNALS OF NEUROLOGY, 1991, 30 (06) :817-824