Substrate modulation of the activity of an artificial nanoesterase made of peptide-functionalized gold nanoparticles

被引:89
作者
Pengo, Paolo
Baltzer, Lars
Pasquato, Lucia
Scrimin, Paolo
机构
[1] Univ Trieste, Dipartimento Sci Chim, I-34127 Trieste, Italy
[2] Univ Padua, Dipartimento Sci Chim, I-35131 Padua, Italy
[3] CNR, ITM, Padova Sect, I-35131 Padua, Italy
[4] Univ Uppsala, Dept Biochem & Organ Chem, S-75105 Uppsala, Sweden
关键词
artificial proteins; gold; hydrolysis; nanoparticles; peptides;
D O I
10.1002/anie.200602581
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanozymes with a heart of gold: A functional artificial protein has been prepared by grafting a dodecapeptide onto the surface of gold nanoparticles (see picture). The system catalyzes the hydrolysis of carboxylate esters and features enzyme-like properties. (Figure Presented). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:400 / 404
页数:5
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