Solubility of paracetamol in binary and ternary mixtures of water plus acetone plus toluene

被引：72

作者：

Granberg, RA ^{[1
]}

Rasmuson, ÅC ^{[1
]}

机构：

[1] Royal Inst Technol, Dept Chem Engn & Technol, SE-10044 Stockholm, Sweden

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2000年 / 45卷 / 03期

关键词：

D O I：

10.1021/je990272l

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility of paracetamol (4-hydroxyacetanilide) in binary mixtures of acetone + water and acetone + toluene and in ternary mixtures of water + acetone + toluene is reported. The temperature range is -5 to +30 degrees C. In acetone + water the solubility increases to a maximum at approximately 25 mass % water before decreasing to a much lower value in pure water as compared to pure acetone. In acetone + toluene the solubility decreases monotonically with increasing toluene concentration. The water content has a strong influence also in ternary mixtures. Activity coefficients in the saturated solutions are estimated.

引用

页码：478 / 483

页数：6

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