ProteomeBinders:: planning a European resource of affinity reagents for analysis of the human proteome

被引:183
作者
Taussig, Michael J. [1 ]
Stoevesandt, Oda
Borrebaeck, Carl A. K.
Bradbury, Andrew R.
Cahill, Dolores
Cambillau, Christian
de Daruvar, Antoine
Duebel, Stefan
Eichler, Jutta
Frank, Ronald
Gibson, Toby J.
Gloriam, David
Gold, Larry
Herberg, Friedrich W.
Hermjakob, Henning
D Hoheisel, Joerg
O Joos, Thomas
Kallioniemi, Olli
Koegll, Manfred
Konthur, Zoltan
Korn, Bernhard
Kremmer, Elisabeth
Krobitsch, Sylvia
Landegren, Ulf
van der Maarel, Silvere
McCafferty, John
Muyldermans, Serge
Nygren, Per-Ake
Palcy, Sandrine
Plueckthun, Andreas
Polic, Bojan
Przybylski, Michael
Saviranta, Petri
Sawyer, Alan
Sherman, David J.
Skerra, Arne
Templin, Markus
Ueffing, Marius
Uhlen, Mathias
机构
[1] Babraham Inst, Technol Res Grp, Cambridge CB22 3AT, England
[2] Lund Univ, Dept Immunotechnol, SE-22184 Lund, Sweden
[3] Los Alamos Natl Lab, Los Alamos, NM 87545 USA
[4] Univ Coll Dublin, Conway Inst, Dublin 4, Ireland
[5] Univ Aix Marseille 1, CNRS, F-13288 Marseille 09, France
[6] Univ Aix Marseille 2, CNRS, F-13288 Marseille 09, France
[7] Univ Bordeaux 2, Ctr Bioinformat, F-33076 Bordeaux, France
[8] Tech Univ Carolo Wilhelmina Braunschweig, Inst Biochem & Biotechnol, D-38106 Braunschweig, Germany
[9] Helmholtz Ctr Infect Res, D-38124 Braunschweig, Germany
[10] European Mol Biol Lab, D-69117 Heidelberg, Germany
[11] European Bioinformat Inst, Cambridge CB10 1SD, England
[12] SomaLogic Inc, Boulder, CO 80301 USA
[13] Univ Kassel, Dept Biochem, D-34132 Kassel, Germany
[14] German Canc Res Ctr, D-69120 Heidelberg, Germany
[15] Univ Tubingen, Nat & Med Sci Inst, D-72770 Tubingen, Germany
[16] Tech Res Ctr Finland, VTT, FIN-20521 Turku, Finland
[17] Resource Ctr Genome Res, D-69120 Heidelberg, Germany
[18] GSF, Natl Res Ctr Environm & Hlth, D-85764 Munich, Germany
[19] Max Planck Inst Mol Genet, D-14195 Berlin, Germany
[20] Uppsala Univ, Dept Genet & Pathol, Rudbeck Lab, SE-75185 Uppsala, Sweden
[21] Leiden Univ, Med Ctr, NL-2300 RC Leiden, Netherlands
[22] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
[23] Vrije Univ Brussels, B-1050 Brussels, Belgium
[24] AlbaNova Univ Ctr, Royal Inst Technol, SE-10691 Stockholm, Sweden
[25] Univ Zurich, Dept Biochem, CH-8057 Zurich, Switzerland
[26] Univ Rijeka, Fac Med, HR-51000 Rijeka, Croatia
[27] Univ Konstanz, Dept Chem, D-78457 Constance, Germany
[28] European Mol Biol Lab, I-00015 Monterotondo, Italy
[29] Lab Bordelais Rech Informat, F-33405 Talence, France
[30] Tech Univ Munich, Lehrstuhl Biol Chem, D-85350 Freising Weihenstephan, Germany
关键词
D O I
10.1038/nmeth0107-13
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
ProteomeBinders is a new European consortium aiming to establish a comprehensive resource of well-characterized affinity reagents, including but not limited to antibodies, for analysis of the human proteome. Given the huge diversity of the proteome, the scale of the project is potentially immense but nevertheless feasible in the context of a pan-European or even worldwide coordination.
引用
收藏
页码:13 / 17
页数:5
相关论文
共 39 条
[1]   Rapid selection of specific MAP kinase-binders from designed ankyrin repeat protein libraries [J].
Amstutz, P ;
Koch, H ;
Binz, HK ;
Deuber, SA ;
Plückthun, A .
PROTEIN ENGINEERING DESIGN & SELECTION, 2006, 19 (05) :219-229
[2]   NIH Molecular Libraries Initiative [J].
Austin, CP ;
Brady, LS ;
Insel, TR ;
Collins, FS .
SCIENCE, 2004, 306 (5699) :1138-1139
[3]   Recombinant protein expression and solubility screening in Escherichia coli:: a comparative study [J].
Berrow, Nick S. ;
Buessow, K. ;
Coutard, B. ;
Diprose, J. ;
Ekberg, M. ;
Folkers, G. E. ;
Levy, N. ;
Lieu, V. ;
Owens, R. J. ;
Peleg, Y. ;
Pinaglia, C. ;
Quevillon-Cheruel, S. ;
Salim, L. ;
Scheich, C. ;
Vincentelli, R. ;
Busso, Didier .
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2006, 62 :1218-1226
[4]   High-affinity binders selected from designed ankyrin repeat protein libraries [J].
Binz, HK ;
Amstutz, P ;
Kohl, A ;
Stumpp, MT ;
Briand, C ;
Forrer, P ;
Grütter, MG ;
Plückthun, A .
NATURE BIOTECHNOLOGY, 2004, 22 (05) :575-582
[5]   Engineering novel binding proteins from nonimmunoglobulin domains [J].
Binz, HK ;
Amstutz, P ;
Plückthun, A .
NATURE BIOTECHNOLOGY, 2005, 23 (10) :1257-1268
[6]   Antibody microarray-based oncoproteomics [J].
Borrebaeck, Carl A. K. .
EXPERT OPINION ON BIOLOGICAL THERAPY, 2006, 6 (08) :833-838
[7]   Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies [J].
De Genst, E ;
Silence, K ;
Decanniere, K ;
Conrath, K ;
Loris, R ;
Kinne, R ;
Muyldermans, S ;
Wyns, L .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (12) :4586-4591
[8]   High throughput production of mouse monoclonal antibodies using antigen microarrays [J].
De Masi, F ;
Chiarella, P ;
Wilhelm, H ;
Massimi, M ;
Belinda, B ;
Ansorge, W ;
Sawyer, A .
PROTEOMICS, 2005, 5 (16) :4070-4081
[9]   Production of soluble mammalian proteins in Escherichia coli:: identification of protein features that correlate with successful expression -: art. no. 32 [J].
Dyson, MR ;
Shadbolt, SP ;
Vincent, KJ ;
Perera, RL ;
McCafferty, J .
BMC BIOTECHNOLOGY, 2004, 4 (1)
[10]   Protein detection using proximity-dependent DNA ligation assays [J].
Fredriksson, S ;
Gullberg, M ;
Jarvius, J ;
Olsson, C ;
Pietras, K ;
Gústafsdóttir, SM ;
Östman, A ;
Landegren, U .
NATURE BIOTECHNOLOGY, 2002, 20 (05) :473-477