ProteomeBinders:: planning a European resource of affinity reagents for analysis of the human proteome

被引：183

作者：

Taussig, Michael J. ^{[1
]}

Stoevesandt, Oda

Borrebaeck, Carl A. K.

Bradbury, Andrew R.

Cahill, Dolores

Cambillau, Christian

de Daruvar, Antoine

Duebel, Stefan

Eichler, Jutta

Frank, Ronald

Gibson, Toby J.

Gloriam, David

Gold, Larry

Herberg, Friedrich W.

Hermjakob, Henning

D Hoheisel, Joerg

O Joos, Thomas

Kallioniemi, Olli

Koegll, Manfred

Konthur, Zoltan

Korn, Bernhard

Kremmer, Elisabeth

Krobitsch, Sylvia

Landegren, Ulf

van der Maarel, Silvere

McCafferty, John

Muyldermans, Serge

Nygren, Per-Ake

Palcy, Sandrine

Plueckthun, Andreas

Polic, Bojan

Przybylski, Michael

Saviranta, Petri

Sawyer, Alan

Sherman, David J.

Skerra, Arne

Templin, Markus

Ueffing, Marius

Uhlen, Mathias

机构：

[1] Babraham Inst, Technol Res Grp, Cambridge CB22 3AT, England

[2] Lund Univ, Dept Immunotechnol, SE-22184 Lund, Sweden

[3] Los Alamos Natl Lab, Los Alamos, NM 87545 USA

[4] Univ Coll Dublin, Conway Inst, Dublin 4, Ireland

[5] Univ Aix Marseille 1, CNRS, F-13288 Marseille 09, France

[6] Univ Aix Marseille 2, CNRS, F-13288 Marseille 09, France

[7] Univ Bordeaux 2, Ctr Bioinformat, F-33076 Bordeaux, France

[8] Tech Univ Carolo Wilhelmina Braunschweig, Inst Biochem & Biotechnol, D-38106 Braunschweig, Germany

[9] Helmholtz Ctr Infect Res, D-38124 Braunschweig, Germany

[10] European Mol Biol Lab, D-69117 Heidelberg, Germany

[11] European Bioinformat Inst, Cambridge CB10 1SD, England

[12] SomaLogic Inc, Boulder, CO 80301 USA

[13] Univ Kassel, Dept Biochem, D-34132 Kassel, Germany

[14] German Canc Res Ctr, D-69120 Heidelberg, Germany

[15] Univ Tubingen, Nat & Med Sci Inst, D-72770 Tubingen, Germany

[16] Tech Res Ctr Finland, VTT, FIN-20521 Turku, Finland

[17] Resource Ctr Genome Res, D-69120 Heidelberg, Germany

[18] GSF, Natl Res Ctr Environm & Hlth, D-85764 Munich, Germany

[19] Max Planck Inst Mol Genet, D-14195 Berlin, Germany

[20] Uppsala Univ, Dept Genet & Pathol, Rudbeck Lab, SE-75185 Uppsala, Sweden

[21] Leiden Univ, Med Ctr, NL-2300 RC Leiden, Netherlands

[22] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[23] Vrije Univ Brussels, B-1050 Brussels, Belgium

[24] AlbaNova Univ Ctr, Royal Inst Technol, SE-10691 Stockholm, Sweden

[25] Univ Zurich, Dept Biochem, CH-8057 Zurich, Switzerland

[26] Univ Rijeka, Fac Med, HR-51000 Rijeka, Croatia

[27] Univ Konstanz, Dept Chem, D-78457 Constance, Germany

[28] European Mol Biol Lab, I-00015 Monterotondo, Italy

[29] Lab Bordelais Rech Informat, F-33405 Talence, France

[30] Tech Univ Munich, Lehrstuhl Biol Chem, D-85350 Freising Weihenstephan, Germany

来源：

NATURE METHODS | 2007年 / 4卷 / 01期

关键词：

D O I：

10.1038/nmeth0107-13

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

ProteomeBinders is a new European consortium aiming to establish a comprehensive resource of well-characterized affinity reagents, including but not limited to antibodies, for analysis of the human proteome. Given the huge diversity of the proteome, the scale of the project is potentially immense but nevertheless feasible in the context of a pan-European or even worldwide coordination.

引用

页码：13 / 17

页数：5

共 39 条

[11]

Gold L., 2006, APTAMER HDB FUNCTION, P461

[12] Cytokine detection by antibody-based proximity ligation [J].

Gullberg, M ;

Gústafsdóttir, SM ;

Schallmeiner, E ;

Jarvius, J ;

Bjarnegård, M ;

Betsholtz, C ;

Landegren, U ;

Fredriksson, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (22) :8420-8424

[13] A reagent resource to identify proteins and peptides of interest for the cancer community - A workshop report [J].

Haab, Brian B. ;

Paulovich, Amanda G. ;

Anderson, N. Leigh ;

Clark, Adam M. ;

Downing, Gregory J. ;

Hermjakob, Henning ;

LaBaer, Joshua ;

Uhlen, Mathias .

MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (10) :1996-2007

[14] In vitro selection and evolution of functional proteins by using ribosome display [J].

Hanes, J ;

Pluckthun, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) :4937-4942

[15]

He Mingyue, 2004, Methods Mol Biol, V248, P177

[16] Antibody-ribosome-mRNA (ARM) complexes as efficient selection particles for in vitro display and evolution of antibody combining sites [J].

He, MY ;

Taussig, MJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (24) :5132-5134

[17] Mating antibody phage display with proteomics [J].

Hust, M ;

Dübel, S .

TRENDS IN BIOTECHNOLOGY, 2004, 22 (01) :8-14

[18] Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides [J].

Knappik, A ;

Ge, LM ;

Honegger, A ;

Pack, P ;

Fischer, M ;

Wellnhofer, G ;

Hoess, A ;

Wölle, J ;

Plückthun, A ;

Virnekäs, B .

JOURNAL OF MOLECULAR BIOLOGY, 2000, 296 (01) :57-86

[19] Perspectives for systematic in vitro antibody generation [J].

Konthur, Z ;

Hust, M ;

Dübel, S .

GENE, 2005, 364 :19-29

[20] Optimal design of microarray immunoassays to compensate for kinetic limitations -: Theory and experiment [J].

Kusnezow, Wlad ;

Syagailo, Yana V. ;

Rueffer, Sven ;

Baudenstiel, Nina ;

Gauer, Christoph ;

Hoheisel, Joerg D. ;

Wild, David ;

Goychuk, Igor .

MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (09) :1681-1696

← 1 2 3 4 →