Transport between ER and Golgi

被引:103
作者
Klumperman, J
机构
[1] Univ Utrecht, Med Ctr, Inst Biomembranes, Dept Cell Biol, NL-3584 CX Utrecht, Netherlands
[2] Univ Utrecht, Med Ctr, Ctr Biomed Genet, NL-3584 CX Utrecht, Netherlands
关键词
D O I
10.1016/S0955-0674(00)00115-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In the last eighteen months, it has become clear that some classes of proteins are actively recruited into endoplasmic reticulum export carriers, whereas others are exported as bulkflow cargo. Subsequent transport to the Golgi is mediated by tubulovesicular membranes. The anterograde membrane flow is compensated for by a retrograde pathway, which, in addition to the recycling of membrane and proteins to the endoplasmic reticulum, may play a role in anterograde cargo concentration.
引用
收藏
页码:445 / 449
页数:5
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