Well-defined, air-stable (NHC)Pd(Allyl)Cl (NHC = N-heterocyclic carbene) catalysts for the arylation of ketones

被引：241

作者：

Viciu, MS ^{[1
]}

Germaneau, RF ^{[1
]}

Nolan, SP ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 23期

关键词：

D O I：

10.1021/ol026745m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A number of palladium-N-heterocyclic carbene (NHC) complexes were found to be active catalysts for the arylation of ketones. A large number of substrates, both aryl halides and ketones, are compatible with the reaction conditions. The ketone arylation reactions are achieved with low catalyst loading in short reaction times using aryl chlorides and triflates; as reactive partners.

引用

页码：4053 / 4056

页数：4

共 37 条

[11]

Herrmann WA, 2002, ANGEW CHEM INT EDIT, V41, P1290, DOI 10.1002/1521-3773(20020415)41:8<1290::AID-ANIE1290>3.0.CO

[12]

2-Y

[13] N-heterocyclic carbenes [J].

Herrmann, WA ;

Kocher, C .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1997, 36 (20) :2162-2187

[14] Catalytic cross-coupling reactions mediated by palladium/nucleophilic carbene systems [J].

Hillier, AC ;

Grasa, GA ;

Viciu, MS ;

Lee, HM ;

Yang, CL ;

Nolan, SP .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2002, 653 (1-2) :69-82

[15]

HILLIER AC, UNPUB ORGANOMETALLIC

[16]

HILLIER AC, 2002, PLATINUM MET REV, V653, P69

[17]

Hillier AC, 2002, PLATIN MET REV, V46, P50

[18] General and efficient catalytic amination of aryl chlorides using a palladium/bulky nucleophilic carbene system [J].

Huang, J ;

Grasa, G ;

Nolan, SP .

ORGANIC LETTERS, 1999, 1 (08) :1307-1309

[19]

Jackstell R, 2002, ANGEW CHEM INT EDIT, V41, P986, DOI 10.1002/1521-3773(20020315)41:6<986::AID-ANIE986>3.0.CO

[20]

2-M

← 1 2 3 4 →