Polybrominated diphenyl ethers in South China maternal and fetal blood and breast milk

被引:286
作者
Bi, Xinhui
Qu, Weiyue
Sheng, Guoying
Zhang, Wenbing
Mai, Bixian
Chen, Dunjin
Yu, Lin
Fu, Jiamo [1 ]
机构
[1] Chinese Acad Sci, State Key Lab Organ Geochem, Guangdong Key Lab Environm & Resources, Inst Geochem, Guangzhou 510640, Peoples R China
[2] Shanghai Univ, Sch Environm & Chem Engn, Shanghai 200072, Peoples R China
[3] Guangzhou Second Peoples Hosp, Obstet & Gynecol Inst, Guangzhou 510150, Peoples R China
基金
中国国家自然科学基金;
关键词
polybrominated diphenyl ethers; contamination; serum; breast milk; China;
D O I
10.1016/j.envpol.2005.12.056
中图分类号
X [环境科学、安全科学];
学科分类号
08 [工学]; 0830 [环境科学与工程];
摘要
Twenty-one-paired human fetal and maternal serum and 27 breast milk samples at South China were analyzed for concentrations of polybrominated diphenyl ethers (PBDEs). Seven PBDE congeners (BDE-28, -47, -99, -100, -153, -154, and -183) were quantified using gas chromatography/mass spectrometry (GC/MS). This is the first report to present the residue levels of PBDEs in human samples of China. The concentrations of total PBDEs ranged from 1.5 to 17 ng/g in the samples and were within the range reported in European samples for a similar population, but lower than human tissue levels in North America. BDE-47 and -153 were the dominant PBDE congeners in all samples and accounted for 60% of the total PBDEs. Further research is needed to determine the exposure route of PBDEs and their health effects. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1024 / 1030
页数:7
相关论文
共 43 条
[1]
Time-trend (1973-2000) of polybrominated diphenyl ethers in Japanese mother's milk [J].
Akutsu, K ;
Kitagawa, M ;
Nakazawa, H ;
Makino, T ;
Iwazaki, K ;
Oda, H ;
Hori, S .
CHEMOSPHERE, 2003, 53 (06) :645-654
[2]
[Anonymous], [No title captured]
[3]
Polybrominated diphenyl ethers: Neurobehavioral effects following developmental exposure [J].
Branchi, I ;
Capone, F ;
Alleva, E ;
Costa, LG .
NEUROTOXICOLOGY, 2003, 24 (03) :449-462
[4]
Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue [J].
Choi, JW ;
Fujimaki, S ;
Kitamura, K ;
Hashimoto, S ;
Ito, H ;
Suzuki, N ;
Sakai, S ;
Morita, M .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2003, 37 (05) :817-821
[5]
Temporal trends of Organochlorine concentrations in umbilical cord blood of newborns from the lower north shore of the St. Lawrence River (Quebec, Canada) [J].
Dallaire, F ;
Dewailly, É ;
Laliberté, C ;
Muckle, G ;
Ayotte, P .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2002, 110 (08) :835-838
[6]
Polybrominated diphenyl ethers:: Occurrence, dietary exposure, and toxicology [J].
Darnerud, PO ;
Eriksen, GS ;
Jóhannesson, T ;
Larsen, PB ;
Viluksela, M .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2001, 109 :49-68
[7]
Monitoring of polychlorinated biphenyls in human blood plasma: Methodological developments and influence of age, lactation, and fish consumption [J].
Grimvall, E ;
Rylander, L ;
NilssonEhle, P ;
Nilsson, U ;
Stromberg, U ;
Hagmar, L ;
Ostman, C .
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1997, 32 (03) :329-336
[8]
Human prenatal and postnatal exposure to polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorobiphenylols, and pentachlorophenol [J].
Guvenius, DM ;
Aronsson, A ;
Ekman-Ordeberg, G ;
Bergman, Å ;
Norén, K .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2003, 111 (09) :1235-1241
[9]
Polybrominated diphenyl ethers in Swedish human liver and adipose tissue [J].
Guvenius, DM ;
Bergman, Å ;
Norén, K .
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2001, 40 (04) :564-570
[10]
Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats - testing interactions and mechanisms for thyroid hormone effects [J].
Hallgren, S ;
Darnerud, PO .
TOXICOLOGY, 2002, 177 (2-3) :227-243