Evolution of the anticonvulsant activity of α-terpineol

被引：85

作者：

de Sousa, Damido Pergentino ^{[1
]}

Quintans, Lucindo, Jr. ^{[1
]}

de Almeida, Reinaldo Nobrega ^{[1
]}

机构：

[1] Univ Fed Paraiba, Lab Tecnol Farmaceut, BR-58051970 Joao Pessoa, Paraiba, Brazil

来源：

PHARMACEUTICAL BIOLOGY | 2007年 / 45卷 / 01期

关键词：

anticonvulsant activity; essential oil; monoterpene; alpha-terpineol;

D O I：

10.1080/13880200601028388

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

alpha-Terpineol, a monoterpenoid alcohol, was investigated for its anticonvulsant activity. This compound increased the latency to convulsions induced by pentylenetetrazole at doses of 100 and 200 mg/kg and decreased the incidence of hindlimb extension produced by MES in a dose-related manner at doses of 200 and 400 mg/kg.

引用

页码：69 / 70

页数：2

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