Distribution of haemophilia in the French Basque country

被引：6

作者：

Bauduer, F ^{[1
]}

Degioanni, A

Ducout, L

Scribans, C

Dutour, O

机构：

[1] Ctr Hosp Cote Basque, Serv Hematol, Dept Haematol, F-64100 Bayonne, France

[2] Univ Mediterranee, UMR 6578, CNRS, Fac Med, Marseille, France

[3] Univ Victor Segalen, Bordeaux, France

来源：

HAEMOPHILIA | 2002年 / 8卷 / 06期

关键词：

Basques; haemophilia; population genetics;

D O I：

10.1046/j.1365-2516.2002.00659.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Because peculiar profiles for some genetic haematological diseases have been described among Basques, we aimed to investigate the distribution of haemophilia among this specific population. Hence, we retrospectively assessed all the cases of factor (F) VIII and FIX deficiencies seen in the French Basque country during a 16-year period. Data on 41 patients with haemophilia (FVIII or FIX = 25%) were compiled. Incidence and prevalence for the whole population ranged within the classical limits (but with an unusually high A : B ratio) and tended to be slightly lower in autochthonous Basques (P = n. s.). Our data did not support significant differences in the distribution of this disease among French Basques.

引用

页码：735 / 739

页数：5

共 22 条

[11] KIM K-Y, 1988, Journal of Korean Medical Science, V3, P107
[12] KOUMBARELIS E, 1994, THROMB HAEMOSTASIS, V72, P808
[13] LARSSON SA, 1982, ACTA MED SCAND, V212, P195
[14] Levine M H, 1977, Ann N Y Acad Sci, V293, P185, DOI 10.1111/j.1749-6632.1977.tb41812.x
[15] Ludlam CA, 2000, HAEMOPHILIA, V6, P494
[16] Moderation of hemophilia A phenotype by the factor V R506Q mutation
Nichols, WC
Amano, K
Cacheris, PM
Figueiredo, MS
Michaelides, K
Schwaab, R
Hoyer, L
Kaufman, RJ
Ginsburg, D
[J]. BLOOD, 1996, 88 (04) : 1183 - 1187
[17] HEMOPHILIA TREATMENT IN HISTORICAL-PERSPECTIVE - A REVIEW OF MEDICAL AND SOCIAL DEVELOPMENTS
ROSENDAAL, FR
SMIT, C
BRIET, E
[J]. ANNALS OF HEMATOLOGY, 1991, 62 (01) : 5 - 15
[18] HEMOPHILIA IN TALMUD AND RABBINIC WRITINGS
ROSNER, F
[J]. ANNALS OF INTERNAL MEDICINE, 1969, 70 (04) : 833 - +
[19] SELIGSOHN U, 1978, BLOOD, V51, P1223
[20] Soria JM, 2001, HAEMATOLOGICA, V86, P889

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