Purealidin S and purpuramine J, bromotyrosine alkaloids from the Fijian marine sponge Druinella sp.

被引：39

作者：

Tabudravu, JN ^{[1
]}

Jaspers, M ^{[1
]}

机构：

[1] Univ Aberdeen, Dept Chem, Marine Nat Prod Lab, Aberdeen AB24 3UE, Scotland

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 12期

关键词：

D O I：

10.1021/np020275n

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

引用

页码：1798 / 1801

页数：4

共 46 条

[41] Pseudoceratidine: A new antifouling spermidine derivative from the marine sponge Pseudoceratina purpurea [J].

Tsukamoto, S ;

Kato, H ;

Hirota, H ;

Fusetani, N .

TETRAHEDRON LETTERS, 1996, 37 (09) :1439-1440

[42] A new dibromotyrosine-derived metabolite from the sponge Psammaplysilla purpurea [J].

Venkateswarlu, Y ;

Rao, MR ;

Venkatesham, U .

JOURNAL OF NATURAL PRODUCTS, 1998, 61 (11) :1388-1389

[43] Novel bromine-containing constituents of the sponge Psammaplysilla purpurea [J].

Venkateswarlu, Y ;

Venkatesham, U ;

Rao, MR .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (06) :893-894

[44] LIPOPUREALINS, NOVEL BROMOTYROSINE DERIVATIVES WITH LONG-CHAIN ACYL-GROUPS, FROM THE MARINE SPONGE PSAMMAPLYSILLA-PUREA [J].

WU, H ;

NAKAMURA, H ;

KOBAYASHI, J ;

OHIZUMI, Y ;

HIRATA, Y .

EXPERIENTIA, 1986, 42 (07) :855-856

[45] 2 NEW BROMOTYROSINE-DERIVED METABOLITES FROM AN AUSTRALIAN MARINE SPONGE, APLYSINA SP [J].

XYNAS, R ;

CAPON, RJ .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1989, 42 (08) :1427-1433

[46] PURPURAMINES A-I, NEW BROMOTYROSINE-DERIVED METABOLITES FROM THE MARINE SPONGE PSAMMAPLYSILLA-PURPUREA [J].

YAGI, H ;

MATSUNAGA, S ;

FUSETANI, N .

TETRAHEDRON, 1993, 49 (18) :3749-3754

← 1 2 3 4 5 →