Role of zinc ion in translational accuracy becomes crystal clear

被引：8

作者：

Musier-Forsyth, K ^{[1
]}

Beuning, PJ ^{[1
]}

机构：

[1] Univ Minnesota, Dept Chem, Minneapolis, MN 55455 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2000年 / 7卷 / 06期

关键词：

D O I：

10.1038/75816

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aminoacyl-tRNA synthetases play a central role in assuring a high degree of accuracy in protein synthesis. New high resolution structures of threonyl-tRNA synthetase bound to threonine or a threonyl-adenylate analog reveal how an active site zinc atom contributes to translational fidelity.

引用

页码：435 / 436

页数：2

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