Synthetic carbohydrate-based vaccines: synthesis of an L-glycero-D-manno-heptose antigen-T-epitope-lipopeptide conjugate

被引：29

作者：

Reichel, F ^{[1
]}

Ashton, PR ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 21期

关键词：

D O I：

10.1039/a704127f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and highly efficient synthesis of a glycopeptidolipid containing a heptose sugar, a synthetic T-epitope and a synthetic immunoadjuvant is presented which represents an important step towards the development of a fully synthetic vaccine against Neisseria meningitidis.

引用

页码：2087 / 2088

页数：2

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