Syntheses of nucleoside triphosphates

被引:178
作者
Burgess, K
Cook, D
机构
[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA
[2] ISIS Pharmaceut, Carlsbad Res Ctr, Carlsbad, CA 92008 USA
关键词
D O I
10.1021/cr990045m
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This review provides a summary of the most useful approaches that have been used to prepare nucleoside triphosphates. The goal is to illustrate the most practical methods for obtaining nucleoside triphosphates and, more importantly, to hint at areas wherein further research might lead to superior approaches. Syntheses of some nucleoside triphosphate analogues are discussed to illustrate how synthetic methods for obtaining nucleoside triphosphates have been applied in different ways.
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页码:2047 / 2059
页数:13
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