Solid-state ion sensors with a liquid junction-free polymer membrane-based reference electrode for blood analysis

被引:48
作者
Yoon, HJ
Shin, JH
Lee, SD
Nam, H
Cha, GS
Strong, TD
Brown, RB
机构
[1] Kwangwoon Univ, Dept Chem, Chem Sensor Res Grp, Nowon Ku, Seoul 139701, South Korea
[2] Univ Michigan, Dept Elect Engn & Comp Sci, Ctr Integrated MicroSyst, Ann Arbor, MI 48109 USA
来源
SENSORS AND ACTUATORS B-CHEMICAL | 2000年 / 64卷 / 1-3期
关键词
ion-selective electrode; all-solid-state ion sensors; liquid junction-free reference electrode; miniaturized ion sensors; polyurethane-based ion-selective membranes;
D O I
10.1016/S0925-4005(99)00476-1
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A set of ion-selective membranes for the measurement of clinically relevant electrolytes, i.e., K+, Na+, Ca2+, H+ and Cl-, and a solvent-processible polyurethane (PU)-based reference membrane were cast on metal electrodes patterned on small ceramic plates, and on silicon-based sensors. Since the liquid junction-free PU membrane-based reference electrode provides a constant potentiometric signal for an extended period of time, accurate determination of blood electrolytes could be made without using a separate reference flow. The PU membrane-based reference electrodes not only improve the mass producibility of miniaturized solid-state ion sensors but also simplify the configuration of flow cell. cartridges without compromising their analytical performance. (C) 2000 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:8 / 14
页数:7
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