Oseltamivir-Resistant Influenza A Pandemic (H1N1) 2009 Virus, Hong Kong, China

被引：83

作者：

Chen, Honglin ^{[1
]}

Cheung, Chung Lam ^{[1
]}

Tai, Hung ^{[1
]}

Zhao, Pengxi ^{[1
]}

Chan, Jasper F. W. ^{[1
]}

Cheng, Vincent C. C. ^{[1
]}

Chan, Kwok-Hung ^{[1
]}

Yuen, Kwok-Yung ^{[1
]}

机构：

[1] Univ Hong Kong, Ctr Infect, Dept Microbiol, Queen Mary Hosp, Pokfulam, Hong Kong, Peoples R China

来源：

EMERGING INFECTIOUS DISEASES | 2009年 / 15卷 / 12期

关键词：

NEURAMINIDASE INHIBITOR; IN-VITRO; INFECTION; CHILDREN; VIVO;

D O I：

10.3201/eid1512.091057

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

引用

页码：1970 / 1972

页数：3

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