Nanoparticle-based energy transfer for rapid and simple detection of protein glycosylation

被引：65

作者：

Oh, Eunkeu

Lee, Dohoon

Kim, Young-Pil

Cha, Seung Youp

Oh, Doo-Beyong

Kang, Hyun Ah

Kim, Jungbae

Kim, Hak-Sung ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Sci Biol, Taejon 305701, South Korea

[2] Korea Res Inst Biosci & Biotechnol, Prot Therapeut Ctr, Taejon 305600, South Korea

[3] Pacific NW Natl Lab, Richland, WA 99352 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 47期

关键词：

carbohydrates; energy transfer; glycoproteins; gold nanoparticles; quantum dots;

D O I：

10.1002/anie.200601948

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Photoluminescence quenching of dextranconjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL = photoluminescence. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

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收藏

页码：7959 / 7963

页数：5

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