Zinc homeostasis and immunity

被引:213
作者
Rink, Lothar [1 ]
Haase, Hajo [1 ]
机构
[1] Univ Hosp, Rhein Westfal TH Aachen, Inst Immunol, D-52074 Aachen, Germany
关键词
D O I
10.1016/j.it.2006.11.005
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Zinc is an essential trace element for the immune system, and zinc deficiency compromises the function of primarily T cells but also of several other immune cells. Recently, zinc homeostasis has been demonstrated to affect dendritic cells, in particular the involvement of zinc transport proteins during lipopolysaccharide-induced upregulation of major histocompatibility complex proteins and co-stimulatory molecules. This adds to our understanding of the immunomodulatory potential of zinc and highlights its significance for immune function.
引用
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页码:1 / 4
页数:4
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