Zinc homeostasis and immunity

被引：213

作者：

Rink, Lothar ^{[1
]}

Haase, Hajo ^{[1
]}

机构：

[1] Univ Hosp, Rhein Westfal TH Aachen, Inst Immunol, D-52074 Aachen, Germany

来源：

TRENDS IN IMMUNOLOGY | 2007年 / 28卷 / 01期

关键词：

D O I：

10.1016/j.it.2006.11.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Zinc is an essential trace element for the immune system, and zinc deficiency compromises the function of primarily T cells but also of several other immune cells. Recently, zinc homeostasis has been demonstrated to affect dendritic cells, in particular the involvement of zinc transport proteins during lipopolysaccharide-induced upregulation of major histocompatibility complex proteins and co-stimulatory molecules. This adds to our understanding of the immunomodulatory potential of zinc and highlights its significance for immune function.

引用

页码：1 / 4

页数：4

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