Anti-influenza virus activity of biflavonoids

被引：89

作者：

Miki, Kazuhiko

Nagai, Takayuki

Suzuki, Kazushige

Tsujimura, Ryo

Koyama, Kiyotaka

Kinoshita, Kaoru

Furuhata, Kimio

Yamada, Haruki

Takahashi, Kunio

机构：

[1] Meiji Pharmaceut Univ, Tokyo 2048588, Japan

[2] Kitasato Inst Life Sci, Minato Ku, Tokyo 1088641, Japan

[3] Kitasato Univ, Grad Sch Infect Control Sci, Minato Ku, Tokyo 1088641, Japan

[4] Kitasato Univ, Oriental Med Res Ctr, Minato Ku, Tokyo 1088642, Japan

[5] Kitasato Univ, Sch Pharm, Minato Ku, Tokyo 1088641, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2007年 / 17卷 / 03期

关键词：

influenza; ginkgetin; sialic acid; Ginkgo biloba; biflavonoid; sialidase;

D O I：

10.1016/j.bmcl.2006.10.075

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Ginkgetin was found to inhibit the influenza virus sialidase. Ginkgetin-sialic acid conjugates showed a significant survival effect in the influenza-virus-infected mice. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：772 / 775

页数：4

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