Progressive multifocal leukoencephalopathy after stem cell transplantation, unsuccessfully treated with cidofovir

被引：29

作者：

Osorio, S

de la Cámara, R

Golbano, N

Marti, E

Fedele, CG

Nieto, S

Manzanares, R

Fernández-Rañada, JM

机构：

[1] Hosp Princesa, Serv Hematol, Dept Hematol, Madrid 28006, Spain

[2] Hosp Princesa, Dept Pathol, Madrid, Spain

[3] Hosp Princesa, Dept Radiol, Madrid, Spain

[4] Inst Carlos III, Ctr Nacl Microbiol, Madrid, Spain

来源：

BONE MARROW TRANSPLANTATION | 2002年 / 30卷 / 12期

关键词：

progressive multifocal leukoencephalopathy; stem cell transplantation; cidofovir;

D O I：

10.1038/sj.bmt.1703704

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We report a patient with progressive multifocal leukoencephalopathy (PML) after autologous stem cell transplantation (SCT) for non-Hodgkin's lymphoma (NHL). This is an unusual association, and to date only seven cases have been reported. This is the first case of PML after SCT treated with cidofovir, and the fifth case treated with this drug in a patient without human immunodeficiency virus (HIV) infection. In the previous four patients treated with cidofovir the outcome was discouraging, as was the case in this patient.

引用

页码：963 / 966

页数：4

共 20 条

[1] PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY - A HITHERTO UNRECOGNIZED COMPLICATION OF CHRONIC LYMPHATIC LEUKAEMIA AND HODGKINS DISEASE [J].