A molecularly imprinted polymer rod as nicotine selective affinity media prepared with 2-(trifluoromethyl)acrylic acid

被引：49

作者：

Matsui, J ^{[1
]}

Takeuchi, T ^{[1
]}

机构：

[1] HIROSHIMA CITY UNIV,FAC INFORMAT SCI,LAB SYNTHET BIOCHEM,ASAMINAMI KU,HIROSHIMA 73131,JAPAN

来源：

ANALYTICAL COMMUNICATIONS | 1997年 / 34卷 / 07期

关键词：

D O I：

10.1039/a703189k

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In situ molecular imprinting was performed using 2-(trifluoromethyl)acrylic acid (TFMAA) as a functional monomer to prepare rod-type affinity media for nicotine in liquid chromatography, The capacity factor of nicotine was 28.4 using an eluent of acetonitrile-acetic acid (98:2, v/v), while a polymer rod prepared by a conventional in situ method, employing methacrylic acid as functional monomer, resulted in a capacity factor of 2.4, showing that TFMAA is useful in in situ molecular imprinting for developing high-affinity chromatographic media.

引用

页码：199 / 200

页数：2

共 11 条

[1] Molecularly imprinted polymers for bioanalysis: Chromatography, binding assays and biomimetic sensors
Ansell, RJ
Kriz, D
Mosbach, K
[J]. CURRENT OPINION IN BIOTECHNOLOGY, 1996, 7 (01) : 89 - 94
[2] UNIFORM-SIZE MACROPOROUS POLYMER-BASED STATIONARY-PHASE FOR HPLC PREPARED THROUGH MOLECULAR IMPRINTING TECHNIQUE
HOSOYA, K
YOSHIZAKO, K
TANAKA, N
KIMATA, K
ARAKI, T
HAGINAKA, J
[J]. CHEMISTRY LETTERS, 1994, (08) : 1437 - 1438
[3] MOLECULAR IMPRINTING USED FOR CHIRAL SEPARATIONS
KEMPE, M
MOSBACH, K
[J]. JOURNAL OF CHROMATOGRAPHY A, 1995, 694 (01) : 3 - 13
[4] ROD-TYPE AFFINITY MEDIA FOR LIQUID-CHROMATOGRAPHY PREPARED BY IN-SITU-MOLECULAR IMPRINTING
MATSUI, J
MIYOSHI, Y
MATSUI, R
TAKEUCHI, T
[J]. ANALYTICAL SCIENCES, 1995, 11 (06) : 1017 - 1019
[5] MOLECULAR RECOGNITION IN CONTINUOUS POLYMER RODS PREPARED BY A MOLECULAR IMPRINTING TECHNIQUE
MATSUI, J
KATO, T
TAKEUCHI, T
SUZUKI, M
YOKOYAMA, K
TAMIYA, E
KARUBE, I
[J]. ANALYTICAL CHEMISTRY, 1993, 65 (17) : 2223 - 2224
[6] MATSUI J, IN PRESS ANAL CHIM A
[7] Molecularly imprinted polymer beads: Suspension polymerization using a liquid perfluorocarbon as the dispersing phase
Mayes, AG
Mosbach, K
[J]. ANALYTICAL CHEMISTRY, 1996, 68 (21) : 3769 - 3774
[8] The emerging technique of molecular imprinting and its future impact on biotechnology
Mosbach, K
Ramstrom, O
[J]. BIO-TECHNOLOGY, 1996, 14 (02): : 163 - 170
[9] IMPRINTED DISPERSION POLYMERS - A NEW CLASS OF EASILY ACCESSIBLE AFFINITY STATIONARY PHASES
SELLERGREN, B
[J]. JOURNAL OF CHROMATOGRAPHY A, 1994, 673 (01) : 133 - 141
[10] Molecular imprinting: An approach to ''tailor-made'' synthetic polymers with biomimetic functions
Takeuchi, T
Matsui, J
[J]. ACTA POLYMERICA, 1996, 47 (11-12) : 471 - 480

← 1 2 →