Membrane properties of sphingomyelins

被引：223

作者：

Ramstedt, B ^{[1
]}

Slotte, JP ^{[1
]}

机构：

[1] Abo Akad Univ, Dept Biochem & Pharm, Turku 20521, Finland

来源：

FEBS LETTERS | 2002年 / 531卷 / 01期

关键词：

cholesterol; lipid interaction; raft property; lipid miscibility; lateral heterogeneity;

D O I：

10.1016/S0014-5793(02)03406-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sphingomyelin and phosphatidylcholine are important components in the external leaflet of cellular plasma membranes. In this review we compare the structure of these lipid molecules, with emphasis on the differences in hydrogen bonding capacity and membrane properties that arise from the small but significant differences in molecular structure. The membrane properties of sphingomyelins and the implications that these have, or might have, in biological membranes and for raft function are further discussed. (C) 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：33 / 37

页数：5

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