Patient-specific isogeometric fluid-structure interaction analysis of thoracic aortic blood flow due to implantation of the Jarvik 2000 left ventricular assist device

被引：313

作者：

Bazilevs, Y. ^{[1
]}

Gohean, J. R. ^{[2
]}

Hughes, T. J. R. ^{[2
]}

Moser, R. D. ^{[2
]}

Zhang, Y. ^{[3
]}

机构：

[1] Univ Calif San Diego, Dept Struct Engn, La Jolla, CA 92093 USA

[2] Univ Texas Austin, Inst Computat Engn & Sci, Austin, TX 78712 USA

[3] Carnegie Mellon Univ, Pittsburgh, PA 15213 USA

来源：

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING | 2009年 / 198卷 / 45-46期

关键词：

Arbitrary Lagrangian-Eulerian (ALE); formulation; Blood flow; Cardiovascular modeling; Fluid-structure interaction; Hyperelastic solids; Incompressible fluids; Isogeometric analysis; Left ventricular assist devices; Mesh movement; Moving domains; NURBS; Oscillatory shear index; Wall shear stress; TIME FINITE-ELEMENTS; WALL SHEAR-STRESS; BOUNDARY-CONDITIONS; ENDOTHELIAL-CELLS; ATHEROSCLEROSIS; NURBS; HEMODYNAMICS; STABILITY; ALGORITHM; PRESSURE;

D O I：

10.1016/j.cma.2009.04.015

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Left ventricular assist devices (LVADs) are continuous flow pumps that are employed in patients with severe heart failure. Although their emergence has significantly improved therapeutic options for patients with heart failure, detailed studies of the impact of LVADs on hemodynamics are notably lacking. To this end we initiate a computational study of the Jarvik 2000 LVAD model employing isogeometric fluid-structure interaction analysis. We focus on a patient-specific configuration in which the LVAD is implanted in the descending thoracic aorta. We perform computations for three pump settings and report our observations for several quantities of hemodynamic interest. It should be noted that this paper presents the first three-dimensional, patient-specific fluid-structure interaction simulation of LVADs. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：3534 / 3550

页数：17

共 59 条

[1] The role of continuity in residual-based variational multiscale modeling of turbulence [J].

Akkerman, I. ;

Bazilevs, Y. ;

Calo, V. M. ;

Hughes, T. J. R. ;

Hulshoff, S. .

COMPUTATIONAL MECHANICS, 2008, 41 (03) :371-378

[2] Isogeometric fluid-structure interaction: theory, algorithms, and computations [J].

Bazilevs, Y. ;

Calo, V. M. ;

Hughes, T. J. R. ;

Zhang, Y. .

COMPUTATIONAL MECHANICS, 2008, 43 (01) :3-37

[3] Variational multiscale residual-based turbulence modeling for large eddy simulation of incompressible flows [J].

Bazilevs, Y. ;

Calo, V. M. ;

Cottrell, J. A. ;

Hughes, T. J. R. ;

Reali, A. ;

Scovazzi, G. .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2007, 197 (1-4) :173-201

[4] Weak Dirichlet boundary conditions for wall-bounded turbulent flows [J].

Bazilevs, Y. ;

Michler, C. ;

Calo, V. M. ;

Hughes, T. J. R. .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2007, 196 (49-52) :4853-4862

[5] Isogeometric analysis:: Approximation, stability and error estimates for h-refined meshes [J].

Bazilevs, Y. ;

Da Veiga, L. Beirao ;

Cottrell, J. A. ;

Hughes, T. J. R. ;

Sangalli, G. .

MATHEMATICAL MODELS & METHODS IN APPLIED SCIENCES, 2006, 16 (07) :1031-1090

[6] Isogeometric fluid-structure interaction analysis with applications to arterial blood flow [J].

Bazilevs, Y. ;

Calo, V. M. ;

Zhang, Y. ;

Hughes, T. J. R. .

COMPUTATIONAL MECHANICS, 2006, 38 (4-5) :310-322

[7] STREAMLINE UPWIND PETROV-GALERKIN FORMULATIONS FOR CONVECTION DOMINATED FLOWS WITH PARTICULAR EMPHASIS ON THE INCOMPRESSIBLE NAVIER-STOKES EQUATIONS [J].

BROOKS, AN ;

HUGHES, TJR .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 1982, 32 (1-3) :199-259

[8] A TIME INTEGRATION ALGORITHM FOR STRUCTURAL DYNAMICS WITH IMPROVED NUMERICAL DISSIPATION - THE GENERALIZED-ALPHA METHOD [J].

CHUNG, J ;

HULBERT, GM .

JOURNAL OF APPLIED MECHANICS-TRANSACTIONS OF THE ASME, 1993, 60 (02) :371-375

[9] Isogeometric analysis of structural vibrations [J].

Cottrell, J. A. ;

Reali, A. ;

Bazilevs, Y. ;

Hughes, T. J. R. .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2006, 195 (41-43) :5257-5296

[10] A computational framework for fluid-structure interaction: Finite element formulation and applications [J].

Dettmer, W. ;

Peric, D. .

COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 2006, 195 (41-43) :5754-5779

← 1 2 3 4 5 6 →