Effect of warm ischemia on graft outcome in laparoscopic donor nephrectomy

被引:32
作者
Simforoosh, N.
Basiri, A.
Shakhssalim, N.
Ziaee, S. A. M.
Tabibi, A.
Moghaddam, S. M. M. Hosseini
机构
[1] Shahid Beheshti Univ Med Sci, Shahid Labba Nejad Hosp, Urol & Nephrol Res Ctr, Dept Urol & Renal Transplantat, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Shahid Labba Nejad Hosp, Urol & Nephrol Res Ctr, Dept Infect Dis & Trop Med, Tehran, Iran
关键词
D O I
10.1089/end.2006.20.895
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: To assess the impact of warm ischemia time (WIT) on delayed graft function (DGF), graft loss, and graft function in laparoscopic donor nephrectomy (LDN). Patients and Methods: We prospectively studied 100 kidney recipients from LDN donors from 2001 to 2003. For comparison of graft outcome with different extents of WIT, recipients were divided into three groups: group A received kidneys having 4 to 6 minutes, group B kidneys having > 6 to 10 minutes, and group C kidneys having > 10 minutes of WIT. The median follow-up was 415 days (range 11-791) days. Results: The mean kidney WIT was 8.7 minutes (range 4-17 minutes). Graft outcome (DGF, graft loss, and median serum creatinine) was not significantly different in the three groups. Conclusions: Different extents of WIT in LDN, within the range of our study, were not associated with an adverse outcome in kidney transplantation.
引用
收藏
页码:895 / 898
页数:4
相关论文
共 22 条
[1]   SURGICAL-TREATMENT OF RENOVASCULAR DISEASE IN THE SOLITARY KIDNEY - RESULTS IN 43 CASES [J].
ASKARI, A ;
NOVICK, AC ;
STEWART, BH ;
STRAFFON, RA .
JOURNAL OF UROLOGY, 1982, 127 (01) :20-22
[2]   Laparoscopic procurement of kidney grafts from living donors does not impair initial renal function [J].
Bettschart, V ;
Vallet, C ;
Golshayan, D ;
Halabi, G ;
Schneider, R ;
Bischof-Delaloye, A ;
Boubaker, A ;
Wauters, JP ;
Mosimann, F .
TRANSPLANTATION PROCEEDINGS, 2002, 34 (03) :787-790
[3]   Warm ischemia time does not correlate with recipient graft function in laparoscopic donor nephrectomy [J].
Buzdon, MM ;
Cho, E ;
Jacobs, SC ;
Jarrell, B ;
Flowers, JL .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2003, 17 (05) :746-749
[4]   Comparison of changes in tissue oxidative-stress markers in experimental model of open, laparoscopic, and retroperitoneoscopic donor nephrectomy [J].
Demirbas, M ;
Samli, M ;
Aksoy, Y ;
Guler, C ;
Kilinc, A ;
Dincel, C .
JOURNAL OF ENDOUROLOGY, 2004, 18 (01) :105-108
[5]   Fate of donor kidney: Laparoscopic versus open technique [J].
Goel, MC ;
Modlin, CS ;
Mottoo, AM ;
Derweesh, IH ;
Flechner, SM ;
Streem, S ;
Gill, I ;
Goldfarb, DA ;
Novick, AC .
JOURNAL OF UROLOGY, 2004, 172 (06) :2326-2330
[6]  
GOES N, 1995, TRANSPLANTATION, V59, P565
[7]   Effect of retroperitoneoscopic donor nephrectomy on tissue oxidative stress markers in rabbit pneumoretroperitoneum model [J].
Guler, C ;
Demirbas, M ;
Samli, M ;
Koken, T ;
Kahraman, A ;
Dincel, C .
JOURNAL OF ENDOUROLOGY, 2003, 17 (10) :935-939
[8]   Predictors of graft outcome in warm ischemically damaged organs [J].
Haisch, C ;
Green, E ;
Brasile, L .
TRANSPLANTATION PROCEEDINGS, 1997, 29 (08) :3424-3425
[9]   ELEVATED INTRA-ABDOMINAL PRESSURE AND RENAL-FUNCTION [J].
HARMAN, PK ;
KRON, IL ;
MCLACHLAN, HD ;
FREEDLENDER, AE ;
NOLAN, SP .
ANNALS OF SURGERY, 1982, 196 (05) :594-597
[10]   RENAL EFFECTS OF CO2 INSUFFLATION - OLIGURIA AND ACUTE RENAL DYSFUNCTION IN A RAT PNEUMOPERITONEUM MODEL [J].
KIRSCH, AJ ;
HENSLE, TW ;
CHANG, DT ;
KAYTON, ML ;
OLSSON, CA ;
SAWCZUK, IS .
UROLOGY, 1994, 43 (04) :453-459