Effect of warm ischemia on graft outcome in laparoscopic donor nephrectomy

被引:32
作者
Simforoosh, N.
Basiri, A.
Shakhssalim, N.
Ziaee, S. A. M.
Tabibi, A.
Moghaddam, S. M. M. Hosseini
机构
[1] Shahid Beheshti Univ Med Sci, Shahid Labba Nejad Hosp, Urol & Nephrol Res Ctr, Dept Urol & Renal Transplantat, Tehran, Iran
[2] Shahid Beheshti Univ Med Sci, Shahid Labba Nejad Hosp, Urol & Nephrol Res Ctr, Dept Infect Dis & Trop Med, Tehran, Iran
关键词
D O I
10.1089/end.2006.20.895
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: To assess the impact of warm ischemia time (WIT) on delayed graft function (DGF), graft loss, and graft function in laparoscopic donor nephrectomy (LDN). Patients and Methods: We prospectively studied 100 kidney recipients from LDN donors from 2001 to 2003. For comparison of graft outcome with different extents of WIT, recipients were divided into three groups: group A received kidneys having 4 to 6 minutes, group B kidneys having > 6 to 10 minutes, and group C kidneys having > 10 minutes of WIT. The median follow-up was 415 days (range 11-791) days. Results: The mean kidney WIT was 8.7 minutes (range 4-17 minutes). Graft outcome (DGF, graft loss, and median serum creatinine) was not significantly different in the three groups. Conclusions: Different extents of WIT in LDN, within the range of our study, were not associated with an adverse outcome in kidney transplantation.
引用
收藏
页码:895 / 898
页数:4
相关论文
共 22 条
[11]   Effect of intravascular volume expansion on renal function during prolonged CO2 pneumoperitoneum [J].
London, ET ;
Ho, HS ;
Neuhaus, AMC ;
Wolfe, BM ;
Rudich, SM ;
Perez, RV .
ANNALS OF SURGERY, 2000, 231 (02) :195-201
[12]   TRANSPLANTATION OF WARM ISCHEMIA DAMAGED KIDNEYS - AN EXPERIMENTAL-STUDY IN PIGS [J].
MORPURGO, E ;
RIGOTTI, P ;
CAPALBO, M ;
BALDAN, N ;
PITTONI, G ;
VALENTE, ML ;
BINDOLI, A ;
ANCONA, E .
RENAL FAILURE, 1993, 15 (05) :581-585
[13]  
NOVICK AC, 1983, UROL CLIN N AM, V10, P637
[14]  
Opelz G, 1998, TRANSPLANT P, V30, P4294
[15]  
RATNER LE, 1995, TRANSPLANTATION, V60, P1047
[16]   Laparoscopic live donor nephrectomy - A review of the first 5 years [J].
Ratner, LE ;
Montgomery, RA ;
Kavoussi, LR .
UROLOGIC CLINICS OF NORTH AMERICA, 2001, 28 (04) :709-+
[17]   Prolonged warm ischemia affects long-term prognosis of kidney transplant allografts from non-heart-beating donors [J].
Shiroki, R ;
Hoshinaga, K ;
Higuchi, T ;
Tsukiashi, Y ;
Kubota, Y ;
Maruyama, T ;
Izumitani, M ;
Horiba, M ;
Naide, Y ;
Kanno, T .
TRANSPLANTATION PROCEEDINGS, 1998, 30 (01) :111-113
[18]   Comparison of laparoscopic and open donor nephrectomy: a randomized controlled trial [J].
Simforoosh, N ;
Basiri, A ;
Tabibi, A ;
Shakhssalim, N ;
Moghaddam, SMMH .
BJU INTERNATIONAL, 2005, 95 (06) :851-855
[19]   A systematic review of laparoscopic live-donor nephrectomy [J].
Tooher, RL ;
Rao, MM ;
Scott, DF ;
Wall, DR ;
Francis, DMA ;
Bridgewater, FHG ;
Maddern, GJ .
TRANSPLANTATION, 2004, 78 (03) :404-414
[20]  
VANES A, 1983, TRANSPLANTATION, V36, P255