Mathematical models of disease transmission: A precious tool for the study of sexually transmitted diseases

被引:27
作者
Boily, MC [1 ]
Masse, B [1 ]
机构
[1] UNIV LAVAL, DEPT SOCIAL & PREVENT MED, QUEBEC CITY, PQ G1K 7P4, CANADA
来源
CANADIAN JOURNAL OF PUBLIC HEALTH-REVUE CANADIENNE DE SANTE PUBLIQUE | 1997年 / 88卷 / 04期
关键词
D O I
10.1007/BF03404793
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
This paper is an introduction to the mathematical epidemiology of sexually transmitted diseases (STDs) and its application to public health. After a brief introduction to transmission dynamics models, the construction of a deterministic compartmental mathematical model of HIV transmission in a population is described. As a background to STD transmission dynamics, basic reproductive rate, inter-group mixing, rate of partner change, and duration of infectivity are discussed. Use of the models illustrates the effect of sexual mixing (proportionate to highly assortative), of preventive intervention campaigns, and of HIV-chlamydia interaction on HIV prevalence in the different population groups. In particular, planned prevention campaigns can benefit the targeted intervention group but surprisingly can be disadvantageous for the general population. Through examples, mathematical models are shown to be helpful in our understanding disease transmission, in interpretation oft observed trends, in planning of prevention strategies, and in guiding data collection.
引用
收藏
页码:255 / 265
页数:11
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