Neuropeptides and chromogranins - Session overview

被引:13
作者
Laslop, A
Mahata, SK
机构
[1] Univ Innsbruck, Dept Pharmacol, A-6020 Innsbruck, Austria
[2] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
来源
CHROMAFFIN CELL: TRANSMITTER BIOSYNTHESIS, STORAGE, RELEASE, ACTIONS, AND INFORMATICS | 2002年 / 971卷
关键词
chromaffin granule; large dense core vesicle; neuroendocrine cells; neuropeptides; chromogranin; secretogranin; regulated secretion;
D O I
10.1111/j.1749-6632.2002.tb04483.x
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In large dense core vesicles, also referred to as chromaffin granules in adrenomedullary chromaffin cells, transmitters or hormones are stored together with neuropeptides and chromogranins. For most neuropeptides, functions have been established and new findings on their secretion, receptors, and synthesis regulation are reported. The functions of chromogranins are less clear, and possible roles as peptide precursors, Ca(2+) regulators, inducers of secretory granule biogenesis, and as nuclear constituents are discussed.
引用
收藏
页码:294 / 299
页数:6
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