Tumor invasion: molecular shears blunted by green tea

被引:164
作者
Garbisa, S [1 ]
Biggin, S
Cavallarin, N
Sartor, L
Benelli, R
Albini, A
机构
[1] Sch Med, Inst Histol & Embryol, I-35121 Padua, Italy
[2] UNIDO ICS, I-34012 Trieste, Italy
[3] CBA, IST, Natl Inst Canc Res, Tumor Progress Sect, Genoa, Italy
[4] CBA, IST, Natl Inst Canc Res, Mol Biol Lab, Genoa, Italy
关键词
D O I
10.1038/15145
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
To the editor–The recent press, both popular and scientific, has given wide coverage of the beneficial properties of green tea, most commonly used in Asian countries. Consumption has been associated with prevention of cancer development and metastasis1. The main flavonol of green tea, epigallocatechin-3-gallate (EGCG), inhibits urokinase2, one of the hydrolases implicated in tumor invasion. Moreover, green tea consumption by mice significantly limits angiogenesis3, crucial for the growth of all solid tumors.
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收藏
页码:1216 / 1216
页数:1
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