LTP mechanisms: from silence to four-lane traffic

被引:316
作者
Malinow, R [1 ]
Mainen, ZF [1 ]
Hayashi, Y [1 ]
机构
[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1016/S0959-4388(00)00099-4
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Brief periods of strong neuronal activity induce long-lasting changes in synaptic function. This synaptic plasticity is thought to play important roles in learning and memory. One example - long-term potentation in the CA1 region of the hippocampus - has been studied extensively, and conflicting views regarding the underlying mechanisms have emerged. Recent findings, regarding basic properties of synaptic transmission, appear to reconcile these diverging views.
引用
收藏
页码:352 / 357
页数:6
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