Absolute stereochemistry of amphidinolides G and H

被引：54

作者：

Kobayashi, J ^{[1
]}

Shimbo, K

Sato, M

Shiro, M

Tsuda, M

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

[2] Rigaku Corp, Xray Res Lab, Tokyo 1968666, Japan

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 18期

关键词：

D O I：

10.1021/ol006223b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Absolute stereochemistry of amphidinolides G (1) and H (2), potent cytotoxic 27- and 26-membered macrolides, respectively, isolated from a marine dinoflagellate Amphidinium sp, was determined by X-ray diffraction analysis, synthesis of a degradation product (3) of 2, and interconversion between 1 and 2.

引用

页码：2805 / 2807

页数：3

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