clpP of Streptococcus salivarius is a novel member of the dually regulated class of stress response genes in gram-positive bacteria

被引:32
作者
Chastanet, A
Msadek, T
机构
[1] Inst Pasteur, Unite Biochim Microbienne, URA 2172, F-75724 Paris 15, France
[2] Ctr Natl Rech Sci, F-75724 Paris, France
关键词
D O I
10.1128/JB.185.2.683-687.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Nucleotide sequence analysis of the Streptococcus salivarius clpP locus revealed potential binding sites for both the CtsR and HrcA repressors. Dual regulation by HrcA and CtsR was demonstrated by using Bacillus subtilis as a heterologous host, and CtsR was shown to bind directly to the clpP promoter sequence. This is the first example of a clpP gene under the control of HrcA.
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页码:683 / 687
页数:5
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